Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 53
Monocarboxylate Transporter-2 Expression Restricts Tumor Growth in a Murine Model of Lung Cancer: A Multi-Omic Analysis.
PMID 34638954 · PMC8508890 · International journal of molecular sciences · 2021 · 8 claims · 8 setups
MCT2 knockout (KO) increases tumor weight, volume, and local invasiveness in the TC1 lung carcinoma model
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Elevated phenylacetylglutamine caused by gut dysbiosis associated with type 2 diabetes increases neutrophil extracellular traps formation and exacerbates brain infarction.
PMID 40471587 · PMC12599254 · Clinical science (London, England : 1979) · 2025 · 7 claims · 8 setups
Plasma PAGln levels are significantly higher in ischemic stroke patients with T2D than in those without T2D
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Has reproduction · 85
TGF-β-dependent reprogramming of amino acid metabolism induces epithelial-mesenchymal transition in non-small cell lung cancers.
PMID 34168290 · PMC8225889 · Communications biology · 2021 · 8 claims · 8 setups
TGF-β induces reprogramming of intracellular amino acid metabolism that is necessary to promote EMT in NSCLC cells
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Diverse Cyanopeptides follow distinct temporal succession patterns in freshwater harmful algal blooms.
PMID 41711085 · PMC13196583 · The ISME journal · 2026 · 8 claims · 7 setups
Shifts from Microcystis to Dolichospermum dominance occur later in the bloom season, coinciding with lower temperatures
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BCAT1-dependent HIF-1α stabilization is a targetable metabolic vulnerability in hepatocellular carcinoma.
PMID 42061407 · PMC13198305 · Cell reports. Medicine · 2026 · 7 claims · 8 setups
BCAT1 depletes α-KG to inhibit PHD and stabilize HIF-1α under hypoxic conditions in HCC
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Small molecule splicing modulators that disrupt O-GlcNAc homeostasis.
PMID 41526361 · PMC12894984 · Nature communications · 2026 · 8 claims · 7 setups
Kinase inhibitors GSK690693 and Y-33075 act as splicing modulators that disrupt O-GlcNAc homeostasis by simultaneously downregulating both OGT and OGA
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Lamin A/C-regulated cysteine catabolic flux modulates stem cell fate through epigenome reprogramming.
PMID 41606307 · PMC12945694 · Nature metabolism · 2026 · 8 claims · 8 setups
Lamin A/C represses cysteine biosynthesis and catabolism in naive mES cells by suppressing CTH and CBS
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Pathway analysis of kidney cancer using proteomics and metabolic profiling.
PMID 17123452 · PMC1665458 · Molecular cancer · 2006 · 8 claims · 8 setups
31 proteins are differentially expressed with high statistical significance (p<0.05) in ccRCC tumor tissue compared to adjacent non-malignant kidney tissue
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Immuno-metabolic dysregulation in type 2 diabetes is associated with altered neutrophil functional plasticity, mitochondrial dysfunction, and compromised responses in sepsis.
PMID 41520116 · PMC12882159 · Journal of translational medicine · 2026 · 8 claims · 8 setups
Proportions of functionally restricted neutrophil subpopulations (phagocytosis-only vs NETosis-only) are significantly altered in T2D and fail to elicit an immune response upon sepsis induction