Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 50
DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency.
PMID 31722211 · PMC6856714 · Cell reports · 2019 · 7 claims · 6 setups
The altered 3D genome of 2i-cultured ESCs (chromatin decompaction and loss of polycomb interactions at polycomb targets) is due to redistribution of polycomb away from its targets.
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Full-text index only
Sequencing DNA methylation and hydroxymethylation at co-occurring chromatin features.
PMID 41667493 · PMC13002996 · Nature communications · 2026 · 8 claims · 8 setups
6-base-CUT&Tag (6B-C&T) simultaneously maps G, A, T, C, 5mC, and 5hmC at antibody-targeted chromatin features on the same DNA fragment