Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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RB loss modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions.
PMID 41951674 · PMC13103356 · Nature communications · 2026 · 8 claims · 8 setups
RB colocalizes extensively with cohesin (SMC3) genome-wide, especially at insulators
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Transient histone deacetylase inhibition induces cellular memory of gene expression and 3D genome folding.
PMID 41639407 · PMC12900649 · Nature genetics · 2026 · 8 claims · 8 setups
Acute HDAC inhibition (TSA pulse) induces genome-wide H3K27 hyperacetylation and reorganizes the histone modification landscape, shifting more of the genome to an active state.
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Modeling nascent transcription from chromatin landscape and structure with CLASTER.
PMID 41691282 · PMC13011747 · Genome biology · 2026 · 7 claims · 8 setups
CLASTER, a deep neural network combining chromatin landscape tracks and 3D contact maps, accurately predicts kilobasepair-resolution nascent RNA (EU-seq) profiles in a DNA-sequence-agnostic manner
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Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs.
PMID 41857393 · PMC13061643 · Nature neuroscience · 2026 · 8 claims · 6 setups
Adult spinal-cord-derived human oligodendroglia and astrocytes, but not microglia, show primed chromatin signatures at HOX loci and a putative SOX10 enhancer.