Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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The development of an integrated platform to identify breast cancer glycoproteome changes in human serum.
PMID 19782370 · PMC4142217 · Journal of chromatography. A · 2010 · 8 claims · 6 setups
M-LAC (multi-lectin affinity chromatography combining Con A, WGA and Jacalin) provides comprehensive capture of glycoproteins from biological fluids based on differing glycan specificities
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Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research.
PMID 20161474 · PMC2794050 · Nature chemistry · 2009 · 8 claims · 7 setups
A parallel combinatorial one-pot multi-step protecting-group procedure (Lewis acid catalyzed, up to seven steps) can transform tetra-O-TMS glucopyranosides into differentially protected monosaccharide building blocks without intermittent work-up/purification
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Proteomic approaches to cancer biomarkers.
PMID 19931265 · PMC2873613 · Gastroenterology · 2010 · 8 claims · 8 setups
Combining abundant-protein depletion, offline fractionation, and subproteome (e.g., glycoproteome) enrichment with 2D LC-MS/MS increases the dynamic range and depth of blood proteome analysis for biomarker discovery.
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Glycomic analysis: an array of technologies.
PMID 19728746 · PMC3443568 · ACS chemical biology · 2009 · 8 claims · 8 setups
Glycosylation is the most prevalent protein post-translational modification, occurring on at least 50% of all proteins