Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 84
An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis.
PMID 36352408 · PMC9648005 · BMC biology · 2022 · 7 claims · 5 setups
A signal transduction/gene regulatory network model of the articular chondrocyte was built combining knowledge-based curation and data-driven (machine learning) network inference
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Full-text index only
Reconstructing transcriptional regulatory networks through genomics data.
PMID 20048387 · PMC3666560 · Statistical methods in medical research · 2009 · 7 claims · 5 setups
Location data (ChIP-chip/ChIP-seq) alone is insufficient for TRN inference because binding does not imply regulation, TF binding is dynamic across conditions/time, and TRNs involve combinatorial effects of multiple TFs not captured by single-TF ChIP experiments.