Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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mtDB: Human Mitochondrial Genome Database, a resource for population genetics and medical sciences.
PMID 16381973 · PMC1347373 · Nucleic acids research · 2006 · 8 claims · 3 setups
mtDB is a comprehensive, actively maintained database of published human mitochondrial genome sequences, providing a common resource for population genetics and medical research
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EGenBio: a data management system for evolutionary genomics and biodiversity.
PMID 17118150 · PMC1683573 · BMC bioinformatics · 2006 · 7 claims · 7 setups
EGenBio is a web-based system for integrated management, filtering, curation, and visualization of large-scale genomic sequences, alignments, and phylogenetic trees for evolutionary genomics and biodiversity research.
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Systems biology of SNPs.
PMID 16820779 · PMC1681509 · Molecular systems biology · 2006 · 8 claims · 2 setups
Co-sets are groups of enzymatic reactions that are perfectly correlated (correlation coefficient of 1) in a reconstructed metabolic network and represent functional modules.
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Expansion of the human mitochondrial proteome by intra- and inter-compartmental protein duplication.
PMID 19930686 · PMC3091328 · Genome biology · 2009 · 8 claims · 6 setups
The human mitochondrial proteome expanded via two prevailing gene duplication modes: intra-mitochondrial and inter-compartmental duplication
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The pseudo-mitochondrial genome influences mistakes in heteroplasmy interpretation.
PMID 16859552 · PMC1538596 · BMC genomics · 2006 · 7 claims · 7 setups
Numts co-amplified with mtDNA during PCR generate false heteroplasmic signals at specific nucleotide positions.
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Polymorphix: a sequence polymorphism database.
PMID 15608242 · PMC540030 · Nucleic acids research · 2005 · 8 claims · 5 setups
Polymorphix is an ACNUC-structured database that organizes EMBL/GenBank sequences into within-species homologous sequence families using similarity and bibliographic criteria, with alignments, outgroups and phylogenetic trees provided.
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From endosymbiont to host-controlled organelle: the hijacking of mitochondrial protein synthesis and metabolism.
PMID 17983265 · PMC2062474 · PLoS computational biology · 2007 · 8 claims · 7 setups
There has been a large turnover of the mitochondrial proteome during evolution: cell envelope synthesis proteins virtually disappeared, and replication, transcription, cell division, transport, regulation, and signal transduction proteins were replaced by eukaryotic proteins
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In Silico screening for functional candidates amongst hypothetical proteins.
PMID 19754976 · PMC2758874 · BMC bioinformatics · 2009 · 7 claims · 6 setups
An in silico selection strategy combining subcellular targeting-signal prediction with protein domain identification can enrich for true functional proteins among hypothetical proteins
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Has reproduction · 65
Estimating biodiversity across the tree of life on Mount Everest's southern flank with environmental DNA.
PMID 36148432 · PMC9486557 · iScience · 2022 · 8 claims · 6 setups
eDNA from ten high-alpine ponds and streams (4,500-5,500 m) on Mt. Everest's southern flank revealed 187 potential orders from 36 phyla across the Tree of Life.
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Has reproduction · 90
CONSULT: accurate contamination removal using locality-sensitive hashing.
PMID 34377979 · PMC8340999 · NAR genomics and bioinformatics · 2021 · 8 claims · 6 setups
CONSULT uses locality-sensitive hashing to test whether query k-mers fall within a user-defined Hamming distance of a reference k-mer database, allowing inexact matching against tens of thousands of microbial species.
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Has reproduction · 68
LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq.
PMID 24709818 · PMC4079972 · Genome research · 2014 · 8 claims · 8 setups
LaSSO (Lariat Sequence Site Origin) identifies intronic lariat reads and pinpoints branch points genome-wide from RNA-seq data by considering every intronic base as a potential branch point and including all possible exon-skipping lariats.
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Human genomic variation.
PMID 11178257 · PMC138878 · Genome biology · 2000 · 8 claims · 7 setups
Lewontin's 1972 analysis of 17 blood-group/protein loci found 85% of human genetic variation lies within individuals of a nation/tribe, 8% between populations within races, and only 6% between races