Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• A single-nucleotide enhancer mutation overrides chromosomal sex to drive XX male development.

  PMID 41957362 · PMC13066550 · Nature communications · 2026 · 8 claims · 7 setups

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  A 3 bp deletion or a 1 bp insertion in the Enh13 SOX9 binding site causes complete XX female-to-male sex reversal in adult homozygous mice

  c57bl6 6-week-old 6-week e12.5 crispr-cas9 gross immunostaining

• The RNA-binding protein SRSF3 controls epicardial formation by regulating splicing and proliferation.

  PMID 41601313 · PMC13006530 · Development (Cambridge, England) · 2026 · 8 claims · 8 setups

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  SRSF3 is highly expressed in the proepicardial organ and early epicardium, declining after E11.5 and remaining low postnatally

  embryo heart e11.5 proepicardium immunofluorescence qrt-pcr conditional

• Modular genetic architecture underlies human hand and foot evolution.

  PMID 42118837 · PMC13187773 · Proceedings of the National Academy of Sciences of the United States of America · 2026 · 8 claims · 8 setups

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  Gene expression and regulatory modules strongly separate metapodials from phalanges, and separate tissues to a lesser extent along the anterior-posterior axis or between limb types

  developing e15.5 chimpanzee developmental rna-seq atac-seq skeletal