Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Developmental stage dominates cell-type identity and reveals a chromatin regulatory function for Rad50 in Drosophila.

  PMID 41978263 · PMC13076223 · Nucleic acids research · 2026 · 8 claims · 8 setups

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  Developmental stage is a stronger determinant of transcriptional identity than cell type across Drosophila neurons, glia, and hemocytes

  neurons cns e16 salivary bulk atac-seq western

• Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans.

  PMID 41481451 · PMC12773780 · Proceedings of the National Academy of Sciences of the United States of America · 2026 · 8 claims · 8 setups

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  Chronic mechanical compression (0.14 kPa) directly induces neuronal apoptosis in human iPSC-derived neurons cocultured with murine glia

  ipsc-derived gfp-expressing mglia astrocytes hoechst gfp+ immunofluorescence

• Excitatory GABA receptors shape locomotor circuit organization in C. elegans.

  PMID 41703147 · PMC13003095 · Scientific reports · 2026 · 8 claims · 5 setups

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  lgc genes are broadly and preferentially enriched in C. elegans locomotion motor neurons compared to other neuron types/subgroups

  elegans cys-loop single-cell ucell multi-species

• bayesReact: expression-coupled regulatory motif analysis detects microRNA activity across cancers, tissues, and at the single-cell level.

  PMID 41657247 · PMC12884093 · Nucleic acids research · 2026 · 8 claims · 6 setups

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  bayesReact is a novel fully Bayesian generative model for inferring regulatory motif (e.g., miRNA) activity from bulk or single-cell expression data

  tcga gtex stem embryonic paired semi-synthetic single-cell

• The H3K36me3 methyltransferase SETD2 contributes to PAF1C interactions with RNA Pol II and is required for neuronal differentiation.

  PMID 41963556 · PMC13187324 · The EMBO journal · 2026 · 8 claims · 8 setups

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  SETD2 is required for establishment of neuronal gene expression during late stages of differentiation but is dispensable in mature neurons

  mesc-derived setd2-fkbp setd2-ko live-dead tet-inducible dtag-based

• Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species.

  PMID 17875208 · PMC2375033 · Genome biology · 2007 · 8 claims · 4 setups

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  A subset of C. elegans DAF-19 target genes have Drosophila homologs that are also regulated by dRFX, showing conservation of the RFX regulatory cascade between the two species.

  drosophila genome melanogaster real-time comparative gfp

• Cross-species prediction reveals chromatin regions with increased accessibility in humans.

  PMID 41984952 · PMC13082337 · Science advances · 2026 · 8 claims · 8 setups

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  CNNs trained exclusively on human ATAC-seq data achieve cross-species prediction performance in chimpanzees and macaques comparable to species-specific models

  lymphoblastoid prefrontal six chimpanzee bulk single-cell cnn