Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Synthetic super-enhancers enable precision viral immunotherapy.
PMID 41951744 · PMC13149004 · Nature · 2026 · 8 claims · 8 setups
Synthetic super-enhancers (SSEs) assembled from validated 160 bp SOX2/SOX9-bound enhancer fragments achieve strong and highly selective transcriptional activity in glioblastoma stem cells (GSCs)
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Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptional and regulatory programs.
PMID 41673768 · PMC12998334 · Journal of experimental & clinical cancer research : CR · 2026 · 6 claims · 8 setups
Organoids derived from malignant effusions of PDAC patients reproducibly generate peritoneal metastases after orthotopic implantation into the pancreas of immunodeficient mice
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Has reproduction · 88
An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying SFPQ-TFE3 driven translocation RCC.
PMID 40463960 · PMC12131257 · iScience · 2025 · 8 claims · 7 setups
SFPQ-TFE3 expression is sufficient to transform normal kidney epithelial tubuloids into tRCC
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MECOM Function Is Critical for AR-Driven Treatment-Resistant Prostate Cancer.
PMID 41529070 · PMC13136877 · Cancer research · 2026 · 7 claims · 8 setups
EVI1, encoded by MECOM, is an AR-recruited coactivator of noncanonical AR signaling in prostate cancer.