Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Engineered apoptotic nucleases for chromatin research.
PMID 17626049 · PMC1935020 · Nucleic acids research · 2007 · 8 claims · 6 setups
Inserting TEVP cleavage sites immediately downstream of the two caspase-3 sites in DFF45 (I1I2 mutant) makes DFF40 nuclease activity exclusively dependent on TEVP cleavage (DFF-T)
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Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals.
PMID 15882449 · PMC1134656 · BMC genomics · 2005 · 8 claims · 4 setups
A predictive computational screen covering ~40% of annotated protein-coding genes identified 21 co-expressed gene clusters with statistically supported sharing of cis-regulatory motifs.
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CompMoby: comparative MobyDick for detection of cis-regulatory motifs.
PMID 18950538 · PMC2605473 · BMC bioinformatics · 2008 · 7 claims · 4 setups
CompMoby identifies cis-regulatory binding sites at both transcriptional and post-transcriptional levels in metazoans without prior knowledge of the trans-acting factor
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Evidence for a preferential targeting of 3'-UTRs by cis-encoded natural antisense transcripts.
PMID 16204454 · PMC1243798 · Nucleic acids research · 2005 · 8 claims · 4 setups
Cis-encoded natural antisense RNAs show striking preferential complementarity to 3′-UTRs of their target genes in human and mouse genomes