Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Atlas of nascent RNA transcripts reveals tissue-specific enhancer to gene linkages.
PMID 40281430 · PMC12032694 · BMC genomics · 2025 · 7 claims · 8 setups
A large repository of nascent run-on RNA-seq samples (DBNascent) was assembled and uniformly processed to identify sites of bidirectional transcription genome-wide.
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Has reproduction · 50
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
PMID 36696508 · PMC9876548 · Science advances · 2023 · 7 claims · 8 setups
Chromatin accessibility continually decreases from mitotic entry until metaphase, then gradually increases as chromosomes segregate.
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Has reproduction · 67
NET-prism enables RNA polymerase-dedicated transcriptional interrogation at nucleotide resolution.
PMID 31156037 · PMC6693550 · RNA biology · 2019 · 8 claims · 7 setups
NET-prism, an adapted NET-seq protocol using immunoprecipitation of Pol II-associated factors, enables strand-specific, nucleotide-resolution interrogation of transcription dynamics for any Pol II-interacting protein.
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OCT4 enhances the firing efficiency of late DNA replication origins in mouse embryonic stem cells.
PMID 41540072 · PMC12910074 · Nature communications · 2026 · 8 claims · 8 setups
In mESCs, a subset of initiation zones (IZs) mapping to mid or late replication-timing (RT) domains fire within 1-2 hours of S-phase entry, much earlier than expected for their RT classification.