Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 4

System / cell line: chip-seq ✕ Assay: native ✕ Clear

Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites.

PMID 41778583 · PMC12959880 · eLife · 2026 · 8 claims · 8 setups

Full-text index only

H3K115ac is enriched at the TSS of active CpG island (CGI) promoters, far more than non-CGI promoters

embryonic mescs synthetic mesc chip-seq atac-seq dot
Bromodomain protein IBD1 bridges histone acetylation and H2A.Z deposition to fine-tune transcription.

PMID 41728948 · PMC12926916 · Nucleic acids research · 2026 · 8 claims · 8 setups

Full-text index only

IBD1's bromodomain recognizes H3K9/K14 di-acetylation to recruit the SWR complex subunit ARP6, ensuring precise H2A.Z incorporation into chromatin

tetrahymena recombinant native cut&tag sequencing
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.

PMID 22955991 · PMC3431496 · Genome research · 2012 · 8 claims · 8 setups

Has reproduction · 74

ENCODE/modENCODE define a set of working standards and guidelines for ChIP-seq covering antibody validation, experimental replication, sequencing depth, data/metadata reporting, and data quality assessment.

small-genome nuclear whole-cell encode chip-seq chip-chip immunoblot
Cell type differences in human cytomegalovirus transcription and epigenetic regulation with insights into major immediate-early enhancer-promoter control.

PMID 40758707 · PMC12333995 · PLoS pathogens · 2025 · 8 claims · 7 setups

Has reproduction · 90

Six viral promoters (UL5, UL72, EP3, UL57-AS, US16-AS, US30-S) are ≥50-fold more active in D-NT2 than in HFF at 96 h post-infection and are classified as viral long promoters.

d-nt2 hcmv-infected hcmv pro-seq dff-chip promoter

Experiments

Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites.

Bromodomain protein IBD1 bridges histone acetylation and H2A.Z deposition to fine-tune transcription.

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.

Cell type differences in human cytomegalovirus transcription and epigenetic regulation with insights into major immediate-early enhancer-promoter control.