Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 9

System / cell line: six ✕ Assay: network ✕ Clear

Reconstruction of human protein interolog network using evolutionary conserved network.

PMID 17493278 · PMC1885812 · BMC bioinformatics · 2007 · 8 claims · 7 setups

Full-text index only

A relative conservation score derived from maximal quasi-cliques in protein interaction networks, combined with other interaction features, can score and rank predicted human interologs for confidence.

ppi sequences interaction predicted interolog orthology quasi-clique
Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in MYOD1-mutant rhabdomyosarcoma.

PMID 41758938 · PMC12947870 · Science advances · 2026 · 7 claims · 8 setups

Has reproduction · 84

MYOD1 L122R-mutant SRMS comprises three coexisting tumor cell states (MYOD1-enriched progenitor-like, proliferative transition, and partially differentiated with reduced MYOD1 activity) reflecting disrupted myogenic differentiation.

six myod1 independent paired single-nucleus targeted bulk
Adaptations to climate in candidate genes for common metabolic disorders.

PMID 18282109 · PMC2242814 · PLoS genetics · 2008 · 8 claims · 7 setups

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A network-based bioinformatics approach (Molecular Triangulation) was used to select 82 candidate genes belonging to the core subnetwork of metabolic syndrome phenotypes.

individuals population genic compiled snp spearman bayesian
Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.

PMID 35922433 · PMC9349177 · Nature communications · 2022 · 8 claims · 7 setups

Has reproduction

Genome-wide association of six CMR-derived aortic traits in up to 32,590 UK Biobank participants identifies 102 loci (including 27 novel associations) for aortic distensibility and area.

biobank arterial aortic genome-wide multi-trait cardiac
Similarities and differences in genome-wide expression data of six organisms.

PMID 14737187 · PMC300882 · PLoS biology · 2004 · 8 claims · 8 setups

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Coexpression of functionally related genes is frequently conserved across evolutionarily distant organisms

saccharomyces caenorhabditis escherichia arabidopsis genome-wide large-scale developmental
Enhancing chemotherapy response prediction via matched colorectal tumor-organoid gene expression analysis and network-based biomarker selection.

PMID 39754813 · PMC11754497 · Translational oncology · 2025 · 6 claims · 8 setups

Has reproduction · 78

A consensus WGCNA approach combining matched tumor-organoid and independent organoid drug-response expression data identifies gene modules and hub genes predictive of 5-FU chemotherapy response

colorectal matched combined expression microarray rna-seq consensus
Discovery and validation of molecular patterns and immune characteristics in the peripheral blood of ischemic stroke patients.

PMID 38650649 · PMC11034498 · PeerJ · 2024 · 8 claims · 8 setups

Has reproduction · 83

188 differentially expressed genes (DEGs) between IS and control blood samples were identified and enriched in immune-related biological pathways

blood degs peripheral hub microarray kegg cibersort
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.

PMID 35870428 · PMC9297827 · EBioMedicine · 2022 · 8 claims · 8 setups

Has reproduction · 85

COVID-19 lung disease resembles IPF at a fundamental level, recapitulating ViP/IPF gene expression patterns, an IL15-centric cytokine storm, and AT2 cytopathic changes (injury, DNA damage, transient progenitor-state arrest, senescence/SASP).

lung covid-19 interaction pre-clinical composite single-cell kaplan-meier
A comparative gene co-expression analysis using self-organizing maps on two congener filmy ferns identifies specific desiccation tolerance mechanisms associated to their microhabitat preference.

PMID 32019526 · PMC7001327 · BMC plant biology · 2020 · 8 claims · 6 setups

Has reproduction · 62

H. caudiculatum (lower canopy) exhibits about twice as many differentially expressed genes as H. dentatum (upper canopy), with a higher proportion of both increased and decreased gene abundance during dehydration.

hymenophyllum dark-adapted annotated differentially bulk relative chlorophyll

Experiments

Reconstruction of human protein interolog network using evolutionary conserved network.

Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in MYOD1-mutant rhabdomyosarcoma.

Adaptations to climate in candidate genes for common metabolic disorders.

Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.

Similarities and differences in genome-wide expression data of six organisms.

Enhancing chemotherapy response prediction via matched colorectal tumor-organoid gene expression analysis and network-based biomarker selection.

Discovery and validation of molecular patterns and immune characteristics in the peripheral blood of ischemic stroke patients.

COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.

A comparative gene co-expression analysis using self-organizing maps on two congener filmy ferns identifies specific desiccation tolerance mechanisms associated to their microhabitat preference.