Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Signals controlling neural crest contributions to the heart.

  PMID 20490374 · PMC2873602 · Wiley interdisciplinary reviews. Systems biology and medicine · 2009 · 8 claims · 8 setups

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  Semaphorin3C (from outflow myocardium) signals through PlexinA2 (on neural crest) to guide cardiac neural crest migration into the outflow tract

  sema3c chick cardiac genetic pharmacologic conditional

• Stage-specific epigenetic priming amplifies gene activation during lineage commitment.

  PMID 41894493 · PMC13025117 · Science advances · 2026 · 8 claims · 8 setups

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  Full-body Msl1 knockout causes embryonic lethality by E10.5, with morphological/developmental delay detectable already at E8.5

  embryos e9.5 mesc-derived bright-field western 10x

• Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.

  PMID 33833454 · PMC7610777 · Nature genetics · 2021 · 8 claims · 8 setups

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  In human embryos, intra-adrenal sympathoblasts are directly derived from nerve-associated Schwann cell precursors (SCPs), similarly to chromaffin cells

  embryo sympathoadrenal embryonic adrenal scrna-seq velocity immunohistochemistry