Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Transient histone deacetylase inhibition induces cellular memory of gene expression and 3D genome folding.
PMID 41639407 · PMC12900649 · Nature genetics · 2026 · 8 claims · 8 setups
Acute HDAC inhibition (TSA pulse) induces genome-wide H3K27 hyperacetylation and reorganizes the histone modification landscape, shifting more of the genome to an active state.
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CITED2 is a druggable epigenetic switch coupling neuronal maturation to regenerative decline.
PMID 41731079 · PMC13083982 · EMBO molecular medicine · 2026 · 8 claims · 8 setups
The transition from immature non-polarized to mature polarized DRG neurons (E12.5-E17.5) is associated with loss of gene expression signatures needed for regenerative growth competence.