Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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EGASP: the human ENCODE Genome Annotation Assessment Project.
PMID 16925836 · PMC1810551 · Genome biology · 2006 · 8 claims · 6 setups
Best-performing computational gene prediction methods correctly predict at least one transcript for close to 70% of annotated genes in the ENCODE regions.
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In silico segmentations of lentivirus envelope sequences.
PMID 17376229 · PMC1847453 · BMC bioinformatics · 2007 · 8 claims · 8 setups
C and V regions of lentivirus SU sequences have distinct statistical (oligonucleotide/amino-acid) compositions that HMMs can learn and use to delimit them.
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Efficient algorithms for probing the RNA mutation landscape.
PMID 18688270 · PMC2475669 · PLoS computational biology · 2008 · 8 claims · 4 setups
RNAmutants generalizes McCaskill's partition function algorithm to sum over the grand canonical ensemble of all secondary structures of all k-point mutants, simultaneously computing MFE(k) and Z(k) for each k
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A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms.
PMID 15592405 · PMC2263125 · Nature · 2004 · 8 claims · 8 setups
A genetic variation map of 2.8 million SNPs was constructed for chicken by comparing 3 domestic breeds to Red Jungle Fowl
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Early feature extraction drives model performance in high-resolution chromatin accessibility prediction.
PMID 41526189 · PMC12951969 · Genome research · 2026 · 8 claims · 6 setups
Early feature extraction (via ConvNeXt V2 blocks), rather than downstream architecture type, is the primary determinant of prediction accuracy in high-resolution chromatin accessibility prediction.
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Comparing whole genomes using DNA microarrays.
PMID 18347592 · PMC7097741 · Nature reviews. Genetics · 2008 · 8 claims · 6 setups
DNA microarrays offer a relatively inexpensive and efficient alternative to genome sequencing for comparing all known classes of genomic diversity between closely related genomes.
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bakR: uncovering differential RNA synthesis and degradation kinetics transcriptome-wide with Bayesian hierarchical modeling.
PMID 37028916 · PMC10275263 · RNA (New York, N.Y.) · 2023 · 8 claims · 4 setups
bakR uses Bayesian hierarchical modeling to share information (specifically a replicate variability vs. read count trend) across transcripts, increasing statistical power for differential kinetic analysis
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Has reproduction · 78
IsomiR_Window: a system for analyzing small-RNA-seq data in an integrative and user-friendly manner.
PMID 33522913 · PMC7852101 · BMC bioinformatics · 2021 · 7 claims · 3 setups
IsomiR Window is a novel integrated pipeline plus browser GUI that combines over ten third-party tools with a new algorithm capable of detecting all types of isomiRs (5' end, 3' end, tailings, SNP/editing, and fuzzy combinations)
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Has reproduction · 83
Gene Expression Atlas update--a value-added database of microarray and sequencing-based functional genomics experiments.
PMID 22064864 · PMC3245177 · Nucleic acids research · 2012 · 8 claims · 5 setups
Gene Expression Atlas is an added-value database providing curated, re-annotated and statistically analysed gene expression data across cell types, organism parts, developmental stages, disease states and other biological/experimental conditions, derived from ArrayExpress Archive and the European Nucleotide Archive.
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Has reproduction · 84
Shifts from cooperative to individual-based predation defense determine microbial predator-prey dynamics.
PMID 36854789 · PMC10119117 · The ISME journal · 2023 · 8 claims · 4 setups
Across all 16 replicate co-cultures of P. putida and P. lacustris, bacteria show a consistent succession of defense strategies over five weeks (~35 predator generations).