Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Tumor suppressor in lung cancer 1 (TSLC1) alters tumorigenic growth properties and gene expression.
PMID 16083501 · PMC1208945 · Molecular cancer · 2005 · 8 claims · 8 setups
Restoration of TSLC1 expression in A549 cells (yielding the 12.2 line) suppresses tumorigenic growth, markedly reducing cell expansion/proliferation rate.
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mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft.
PMID 18980691 · PMC2612029 · BMC genomics · 2008 · 8 claims · 8 setups
mtDNA depletion confers specific, shared gene expression profiles in A549 cells grown in culture and as xenografts
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Mutations in the focal adhesion targeting region of deleted in liver cancer-1 attenuate their expression and function.
PMID 18829524 · PMC2597479 · Cancer research · 2008 · 8 claims · 6 setups
The DLC-1 fragment spanning residues 201-500 is sufficient for focal adhesion targeting (FAT region)
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Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations.
PMID 16789823 · PMC1513265 · PLoS genetics · 2006 · 8 claims · 8 setups
K63-polyubiquitin chain formation protects human cells against translesion synthesis-induced mutations by promoting error-free recovery of blocked replication forks.
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Has reproduction · 71
Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF+ tumor cells and the therapeutic potential of FOS.
PMID 40936936 · PMC12420628 · Frontiers in immunology · 2025 · 7 claims · 8 setups
A highly stem-like C0 MAFF+ tumor cell subtype dominates invasive LUAD, producing chemokines and activating lipid metabolism
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Identification of biofilm-associated cluster (bac) in Pseudomonas aeruginosa involved in biofilm formation and virulence.
PMID 19065261 · PMC2587700 · PloS one · 2008 · 8 claims · 8 setups
A ΔpA3731 mutant is highly biofilm-defective on abiotic (polystyrene) and biotic (A549 pneumocyte) surfaces compared with wild-type PAO1
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Cellular proteins in influenza virus particles.
PMID 18535660 · PMC2390764 · PLoS pathogens · 2008 · 8 claims · 6 setups
Purified influenza virions contain 36 host-encoded cellular proteins in addition to the 9 previously known viral proteins.
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Has reproduction · 100
Betacoronavirus-specific alternate splicing.
PMID 35074468 · PMC8782732 · Genomics · 2022 · 8 claims · 8 setups
Genes showing differential alternative splicing in SARS-CoV-2 have a similar functional profile to those in SARS-CoV and MERS, affecting a diverse set of genes and biological functions related to virus biology.
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Has reproduction · 59
Downregulation of Splicing Factor PTBP1 Curtails FBXO5 Expression to Promote Cellular Senescence in Lung Adenocarcinoma.
PMID 39057099 · PMC11276454 · Current issues in molecular biology · 2024 · 8 claims · 8 setups
PTBP1 is significantly upregulated across multiple cancer types including LUAD, and higher PTBP1 levels are associated with worse LUAD patient survival
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Has reproduction · 88
Constructing an APOBEC-related gene signature with predictive value in the overall survival and therapeutic sensitivity in lung adenocarcinoma.
PMID 37954334 · PMC10637964 · Heliyon · 2023 · 8 claims · 8 setups
APOBEC family genes are aberrantly expressed across cancers, with APOBEC3B the most consistently upregulated, and APOBEC3B/APOBEC3A are markedly altered in LUAD