Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network.
PMID 42020373 · PMC13102947 · Nature communications · 2026 · 8 claims · 8 setups
TBL/R1 are crucial regulators of β-cell identity and determinants of diabetes development and progression
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Has reproduction · 70
The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease.
PMID 38839750 · PMC11153611 · Nature communications · 2024 · 8 claims · 8 setups
Intestinal epithelial cell-specific deletion of Slc39a8 causes systemic Mn deficiency in blood and multiple organs
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Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma.
PMID 41644942 · PMC12895007 · Cell death discovery · 2026 · 7 claims · 13 setups
NXP800 decreases viability of osteosarcoma cell lines by blocking proliferation and inducing apoptosis
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Has reproduction
Ligilactobacillus salivarius regulating translocation of core bacteria to enrich mouse intrinsic microbiota of heart and liver in defense of heat stress.
PMID 40276518 · PMC12018310 · Frontiers in immunology · 2025 · 6 claims · 6 setups
Intrinsic microbiota (dominated by Burkholderia and Ralstonia) resides in the heart and liver of healthy SPF mice
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A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer.
PMID 41128661 · PMC12877754 · Cancer discovery · 2026 · 8 claims · 8 setups
RMC-9945 exerts durable antitumor activity in early-stage liver metastasis but has diminished therapeutic effect in advanced metastatic disease
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An AIB1 isoform rewires glucocorticoid receptor signaling to promote TNBC progression.
PMID 41704785 · PMC12907120 · iScience · 2026 · 8 claims · 10 setups
GR antagonists (RU486, relacorilant) inhibit AIB1Δ4-driven invasion of DCIS cells in 3D invasion assays, zebrafish extravasation, and mouse xenograft models
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Glutamine-mediated crosstalk between M2 macrophages and tumor cells via the SLC38A5/FOXM1/CNIH4 axis promotes oral squamous cell carcinoma progression.
PMID 41715179 · PMC13020291 · Journal of translational medicine · 2026 · 8 claims · 8 setups
Glutamine secretion from M2 macrophages to tumor cells via SLC38A5 is the core mCCC pathway upregulated in metastatic OSCC lesions compared to primary lesions.
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Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs.
PMID 41770903 · PMC13078882 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups
A commensal Ascomycota fungus, Engyodontium sp., was isolated live from mouse feces using a Dectin-2-Fc fusion protein
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Targeting the Lipid Metabolism Proteins FASN and GPAM in Alveolar Type II Cells Decreases Lung Metastasis.
PMID 41778850 · PMC7619144 · Cancer discovery · 2026 · 7 claims · 8 setups
AT2 cells and surfactant lipids (e.g., PC, PE, PI, PG) are enriched in the vicinity of breast cancer lung metastases in both patients and mice