Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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The key role of genomics in modern vaccine and drug design for emerging infectious diseases.
PMID 19855822 · PMC2752168 · PLoS genetics · 2009 · 8 claims · 8 setups
Reverse vaccinology (in silico genome screening for surface/secreted proteins) can identify vaccine candidates far faster than conventional approaches, as demonstrated by the MenB project.
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Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity.
PMID 16301741 · PMC2212990 · The Journal of experimental medicine · 2005 · 8 claims · 8 setups
S. mansoni eggs secrete a chemokine binding protein (smCKBP) that binds certain chemokines and inhibits their interaction with host chemokine receptors and biological activity
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High throughput sequencing and proteomics to identify immunogenic proteins of a new pathogen: the dirty genome approach.
PMID 20037647 · PMC2793016 · PloS one · 2009 · 7 claims · 7 setups
A dirty genome approach using unfinished, unclosed genome sequences combined with proteomics can rapidly identify immunogenic proteins useful for diagnostic tool development
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A catalog of human cDNA expression clones and its application to structural genomics.
PMID 15345055 · PMC522878 · Genome biology · 2004 · 8 claims · 7 setups
A high-throughput screening approach can identify human cDNA clones from the hEx1 library that express soluble protein in E. coli