Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Histone methyl-transferase G9a inhibition boosts the efficacy of immune checkpoint inhibitors in experimental hepatocellular carcinoma.
PMID 41923620 · PMC13130624 · Cell reports. Medicine · 2026 · 7 claims · 8 setups
G9a expression inversely correlates with gene signatures predictive of favorable ICI response across multiple HCC patient cohorts
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Hypoxia-driven remodeling of SELENOP(+) macrophages shapes T cell dynamics and promotes ovarian cancer metastasis.
PMID 41526347 · PMC12852879 · Nature communications · 2026 · 8 claims · 8 setups
SELENOP+ macrophages co-occur and spatially co-localize with precursor exhausted (GZMH+) CD8+ T cells and activate these T cells via selenoprotein P in vitro and in vivo.
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Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.
PMID 20400112 · PMC2907433 · The Journal of surgical research · 2011 · 8 claims · 8 setups
ROS/RNS generated during hepatic ischemia/reperfusion cause cellular damage via mitochondrial dysfunction, ATP depletion, ion disturbances, and membrane/lysosomal disruption
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Spatial multi-omics identifies a NOTCH3-mediated capillary-mCAF crosstalk driving immune exclusion in hepatocellular carcinoma.
PMID 42099451 · PMC13147954 · iMeta · 2026 · 8 claims · 8 setups
A high-resolution spatial multi-omics atlas of HCC (CosMx transcriptomics + GeoMx proteomics + pan-cancer scRNA-seq of CAFs under ICB) reveals coordinated cellular topography of the tumor microenvironment