Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Differentiating Drosophila female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins.

  PMID 32773039 · PMC7438113 · eLife · 2020 · 8 claims · 2 setups

  Has reproduction · 87

  Germline stem cells (GSCs) have a non-canonical PRC2 distribution and lack silenced chromatin, resembling early embryonic progenitors

  drosophila facs-purified hsgfp chipseq

• Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma.

  PMID 19654294 · PMC2754824 · Cancer research · 2009 · 8 claims · 7 setups

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  Secondary BRCA2 mutations restore BRCA2 protein/reading frame and thereby cause acquired platinum and PARP inhibitor resistance in BRCA2-mutated ovarian carcinoma

  ovarian peo1 v-c8-dr-gfp western brca2 crystal

• Keratin 5 marks cancer-propagating cells sustained by an osteopontin-producing niche in high-grade serous ovarian carcinoma.

  PMID 42111394 · PMC13155427 · Cancer heterogeneity and plasticity · 2026 · 8 claims · 8 setups

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  KRT5+ cells represent bona fide cancer-propagating cells (CPCs) in HGSC

  hgsc skov3 facs-sorted nod immunohistochemistry lentiviral organoid

• Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy.

  PMID 41872134 · PMC13039919 · Cell death discovery · 2026 · 8 claims · 8 setups

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  Prostaglandin-mediated immunosuppressive microenvironment formation is a critical contributor to chemotherapy resistance following cisplatin treatment

  high-grade hgsoc bone bmdms scrna-seq cell-cell tensor

• Mod(mdg4) variants repress telomeric retrotransposon HeT-A by blocking subtelomeric enhancers.

  PMID 36373634 · PMC9723646 · Nucleic acids research · 2022 · 8 claims · 8 setups

  Has reproduction · 68

  Specific splice variants of Mod(mdg4) repress HeT-A by blocking subtelomeric enhancers in ovarian somatic cells (OSCs)

  drosophila ovarian osc melanogaster chip-seq sirna western

• Engineering NK and T cells with metabolite-sensing receptors to target solid tumors.

  PMID 41872506 · PMC13132725 · Nature immunology · 2026 · 8 claims · 8 setups

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  GPR183, GPR84, GPR34 and GPR18 were identified as top enhancers of NK cell tumor infiltration and chemotaxis to breast and ovarian cancer via CRISPRa screens

  nk-92 reporter tumor crispra large-scale transwell

• In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells.

  PMID 32665556 · PMC7360550 · Nature communications · 2020 · 8 claims · 8 setups

  Has reproduction · 50

  Cancer cells in vivo display higher coherent orientation of MT dynamics along their major axis compared to 2D in vitro cultures

  ht1080-eb3-mapple es2-eb3-mapple ht1080 cancer intravital live-cell confocal

• MEIOC prevents continued mitotic cycling and promotes meiotic entry during mouse oogenesis.

  PMID 41287933 · PMC12848572 · Development (Cambridge, England) · 2026 · 8 claims · 4 setups

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  MEIOC prevents continued mitotic cycling in preleptotene oocytes prior to meiotic entry

  e16.5 e14.5 ovarian edu bulk single-cell