Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Report on the Molecular Approaches to Osteoarthritis Symposium, Imperial College London, UK, 18-20 April 2004.
PMID 15380034 · PMC546282 · Arthritis research & therapy · 2004 · 8 claims · 8 setups
OA cartilage and synovium show an 'IL-1 signature' of upregulated inflammatory cytokines/chemokines, with peripheral blood leukocytes possibly activated by trafficking through affected joints
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Personalized medicine: the future is not what it used to be.
PMID 19958922 · PMC2844719 · Surgery · 2009 · 8 claims · 8 setups
Many rare tumors harbor a genomic Achilles heel that can be exploited for targeted therapy
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Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.
PMID 20400112 · PMC2907433 · The Journal of surgical research · 2011 · 8 claims · 8 setups
ROS/RNS generated during hepatic ischemia/reperfusion cause cellular damage via mitochondrial dysfunction, ATP depletion, ion disturbances, and membrane/lysosomal disruption
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Has reproduction · 94
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
PMID 38167725 · PMC10762034 · Nature communications · 2024 · 7 claims · 8 setups
FASN activity critically determines the use/incorporation of dietary PUFA into complex lipids in mice and humans
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From single cells to whole organisms.
PMID 16420683 · PMC1414103 · Genome biology · 2005 · 8 claims · 8 setups
The genetic-interaction map in S. cerevisiae is roughly four times as complex as the protein-protein interaction map, and genetic interactions do not overlap with physical interactions but instead predict functional neighborhoods
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Has reproduction · 69
Understanding the function of Pax5 in development of docetaxel-resistant neuroendocrine-like prostate cancers.
PMID 39183332 · PMC11345443 · Cell death & disease · 2024 · 7 claims · 8 setups
Pax5 is an important transcription factor driving neuronal gene expression and is specific to t-NEPC