Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Comparative phosphoproteomics reveals evolutionary and functional conservation of phosphorylation across eukaryotes.
PMID 18828897 · PMC2760871 · Genome biology · 2008 · 8 claims · 8 setups
The overlap between phosphoproteomes of six eukaryotes (human, mouse, fly, yeast, plant, zebrafish) is significantly greater than expected by chance.
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Has reproduction · 68
LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq.
PMID 24709818 · PMC4079972 · Genome research · 2014 · 8 claims · 8 setups
LaSSO (Lariat Sequence Site Origin) identifies intronic lariat reads and pinpoints branch points genome-wide from RNA-seq data by considering every intronic base as a potential branch point and including all possible exon-skipping lariats.
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Fast and systematic genome-wide discovery of conserved regulatory elements using a non-alignment based approach.
PMID 15693947 · PMC551538 · Genome biology · 2005 · 7 claims · 8 setups
FastCompare, a non-alignment-based, linear-time algorithm, computes a genome-wide conservation score for all k-mers (7-9 nt) between two genomes to identify conserved regulatory elements
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Defining the proteome.
PMID 16356278 · PMC1414090 · Genome biology · 2005 · 8 claims · 8 setups
Integration of multi-omics data is an important step toward a systems-biology approach to the proteome
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InSite: a computational method for identifying protein-protein interaction binding sites on a proteome-wide scale.
PMID 17868464 · PMC2375030 · Genome biology · 2007 · 8 claims · 8 setups
InSite predicts protein-pair-specific binding motifs ('Motif M on protein A binds to protein B') by integrating heterogeneous PPI and motif-motif interaction evidence within a Bayesian network trained by EM
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A map of human protein interactions derived from co-expression of human mRNAs and their orthologs.
PMID 18414481 · PMC2387231 · Molecular systems biology · 2008 · 8 claims · 6 setups
Comparing human mRNA co-expression with co-expression of orthologous gene pairs in five other organisms identifies proteins that physically associate
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The use of edge-betweenness clustering to investigate biological function in protein interaction networks.
PMID 15740614 · PMC555937 · BMC bioinformatics · 2005 · 8 claims · 7 setups
Edge-Betweenness clustering separates protein interaction graphs into subgraphs whose GO term distributions show significant correlations, revealing biologically meaningful functional modules.
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HUPO Highlights.
PMID 19862759 · PMC4594800 · Proteomics · 2009 · 8 claims · 8 setups
Mass spectrometry analysis of human liver reference samples (French Reference liver + Huh7 hepatoma cells) achieves substantial human genome coverage via PeptideAtlas processing