Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Diminutive, degraded but dissimilar: Wolbachia genomes from filarial nematodes do not conform to a single paradigm.

  PMID 33295865 · PMC8116671 · Microbial genomics · 2020 · 8 claims · 4 setups

  Has reproduction · 98

  wCtub and wDcau (863 988 bp and 863 427 bp) are the smallest Wolbachia genomes sequenced to date and are the first genomes representing supergroup J.

  wolbachia filarial six target-enrichment whole-genome novo

• A haplotype-complete chromosome-level assembly of octoploid Urochloa humidicola cv. Tully reveals multiple genomic compositions and evolutionary histories in the species.

  PMID 41678351 · PMC13042314 · G3 (Bethesda, Md.) · 2026 · 8 claims · 8 setups

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  A haplotype-complete, chromosome-level genome assembly of octoploid U. humidicola cv. Tully was generated from PacBio HiFi reads alone

  humidicola chromosomes urochloa additional pacbio busco proteome

• Alternative splicing-triggered mRNA decay informs splice-switching targets for neurodevelopmental disorders.

  PMID 41678398 · PMC13078869 · The Journal of clinical investigation · 2026 · 7 claims · 12 setups

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  EANMD, a new computational tool, identifies AS-NMD exons using the 50 nt rule plus additional transcript-level features and outperforms existing tools (SpliceTools, NMD Classifier)

  neuro2a embryonic e14.5 cortical rna-seq pacbio rt-pcr

• Isoform-specific single-cell perturb-seq reveals distinct functions of alternative promoters in drug response.

  PMID 41728950 · PMC12926921 · Nucleic acids research · 2026 · 5 claims · 8 setups

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  CRISPR-dCas9-based screens exhibit widespread promoter specificity, with untargeted promoters often showing compensatory upregulation to maintain overall gene expression

  mcf-7 rpe1 mcf-7-dcas9 tissue-wide isoform-specific reanalysis qrt-pcr