Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Evidence for limited genetic compartmentalization of HIV-1 between lung and blood.
PMID 19759830 · PMC2736399 · PloS one · 2009 · 8 claims · 7 setups
Statistical evidence of genetic compartmentalization between lung and blood HIV-1 env sequences was found in 10 of 18 subjects.
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Dynamics of intronic polyadenylation in the hematopoietic lineage and its regulation by DNA methylation.
PMID 41974581 · PMC13262950 · Genome research · 2026 · 8 claims · 5 setups
IPAseek, a dynamic programming framework combining the PELT algorithm with CROPS, enables de novo identification of IPA events from bulk RNA-seq data.
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Spatially resolved integrative analysis of transcriptomic and metabolomic changes in tissue injury studies.
PMID 41501078 · PMC12780049 · Nature communications · 2026 · 8 claims · 7 setups
MAGPIE is a computational framework (Snakemake workflow) that co-registers Visium spatial transcriptomics with MSI metabolomics and tissue morphology images from same or consecutive sections
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Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs.
PMID 41857393 · PMC13061643 · Nature neuroscience · 2026 · 8 claims · 6 setups
Adult spinal-cord-derived human oligodendroglia and astrocytes, but not microglia, show primed chromatin signatures at HOX loci and a putative SOX10 enhancer.
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HIF sustain a transcriptional regulatory circuit of EPAS1 expression in renal clear cell carcinoma.
PMID 41714613 · PMC12921326 · Nature communications · 2026 · 8 claims · 8 setups
HIF-2α mRNA is specifically overexpressed in ccRCC tumor tissue/cells compared to normal kidney, while it is reduced in papillary and chromophobe RCC
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Has reproduction · 68
Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter.
PMID 38587191 · PMC11077057 · Nucleic acids research · 2024 · 6 claims · 8 setups
A dual fluorescence (GFP-mCherry) readthrough reporter with a PAS inserted between the two reporters enables measurement of 3' end processing efficiency in living cells.