Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 83
ConNIS and labeling instability: New statistical methods for improving the detection of essential genes in TraDIS libraries.
PMID 41790830 · PMC12991369 · PLoS computational biology · 2026 · 8 claims · 3 setups
ConNIS provides an analytic solution for the probability of observing the longest insertion-free sequence within a gene given its length and number of insertion sites under non-essentiality.
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Full-text index only
FeatureScan: revealing property-dependent similarity of nucleotide sequences.
PMID 16845077 · PMC1538849 · Nucleic acids research · 2006 · 6 claims · 5 setups
FeatureScan transforms nucleotide sequences into numerical signals of physico-chemical/conformational properties and compares them via a convolution/correlation (Fourier transform) method rather than comparing letters
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Full-text index only
Threshold-dominated regulation hides genetic variation in gene expression networks.
PMID 18062810 · PMC2238762 · BMC systems biology · 2007 · 8 claims · 2 setups
Threshold robustness (insensitivity of a singular/regulating variable's equilibrium value to parameter perturbations, except threshold changes) increases with increasing response function steepness and is present even under Michaelis-Menten conditions, not just in the step-function limit.
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Has reproduction · 73
Gapless provides combined scaffolding, gap filling, and assembly correction with long reads.
PMID 37142439 · PMC10166144 · Life science alliance · 2023 · 8 claims · 5 setups
gapless is a new tool that combines assembly correction, scaffolding, and gap filling in one pipeline using PacBio or Oxford Nanopore long reads.
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Has reproduction · 45
Identifying and classifying trait linked polymorphisms in non-reference species by walking coloured de bruijn graphs.
PMID 23536903 · PMC3607606 · PloS one · 2013 · 8 claims · 9 setups
Bubbleparse detects sequence variants directly from NGS reads without a reference genome, using the coloured de Bruijn graph implementation of Cortex plus a new depth-first bubble-finding module.