Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 6

System / cell line: normal ✕ Assay: partial ✕ Clear

Understanding the mechanisms of drug-associated interstitial lung disease.

PMID 15340376 · PMC2750813 · British journal of cancer · 2004 · 8 claims · 7 setups

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Apoptosis of alveolar/bronchial epithelial cells via Fas-FasL and mitochondrial (cytochrome c/caspase-9) pathways is a key mechanism underlying drug-, chemotherapy-, and radiation-associated lung injury and fibrosis

bronchial lung swiss mice immunohistochemistry toxicology pulmonary
Testing whether genetic variation explains correlation of quantitative measures of gene expression, and application to genetic network analysis.

PMID 18444230 · PMC2729096 · Statistics in medicine · 2008 · 8 claims · 3 setups

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A statistical test (delta method and Steiger-Browne optimal linear composites) is developed to test equality of the marginal correlation and the partial correlation of two gene expression traits conditional on a set of covariates.

simulated real analytical simulation application
Network inference and network response identification: moving genome-scale data to the next level of biological discovery.

PMID 20174676 · PMC3087299 · Molecular bioSystems · 2010 · 8 claims · 8 setups

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Cellular response to a signal is assumed to involve only specific TRN modules (conditionally active subnetworks) rather than the entire network, providing quantitative tractability

yeast specified normal coli chip-on-chip chip-sequencing correlation-based
Genetic alterations in the coding region of the bak gene in uterine cervical carcinoma.

PMID 12771926 · PMC2377111 · British journal of cancer · 2003 · 8 claims · 3 setups

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A significant frequency of mutations (six missense, one silent) was found in the coding region of the bak gene (exons 3, 4, 6) in uterine cervical carcinoma

uterine non-neoplastic stage pcr-sscp clinical
The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions.

PMID 12036445 · PMC5927037 · Japanese journal of cancer research : Gann · 2002 · 8 claims · 5 setups

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SNI (elevated spontaneous point mutation rate without microsatellite instability) is present in rat mammary carcinoma cell lines and human breast cancer cell lines

mammary same normal pcr-sscp direct quantitative
Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis.

PMID 12908878 · PMC194569 · BMC genomics · 2003 · 8 claims · 7 setups

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XRRA1 is a novel gene down-regulated ~2-fold in XR-resistant HCT116 Clone2_XRR relative to HCT116 Clone10, identified via cDNA microarray

hct116 macaque cos-7 genomic cdna est molecular

Experiments

Understanding the mechanisms of drug-associated interstitial lung disease.

Testing whether genetic variation explains correlation of quantitative measures of gene expression, and application to genetic network analysis.

Network inference and network response identification: moving genome-scale data to the next level of biological discovery.

Genetic alterations in the coding region of the bak gene in uterine cervical carcinoma.

The absence of Mth1 inactivation and DNA polymerase kappa overexpression in rat mammary carcinomas with frequent A:T to C:G transversions.

Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis.