Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Improvements to cardiovascular gene ontology.
PMID 19046747 · PMC2706316 · Atherosclerosis · 2009 · 8 claims · 8 setups
Gene Ontology (GO) provides a controlled vocabulary that links current functional knowledge of genes to high-throughput genomic and proteomic datasets, aiding data interpretation.
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Massively parallel pyrosequencing in HIV research.
PMID 18614863 · PMC4221253 · AIDS (London, England) · 2008 · 8 claims · 8 setups
Massively parallel pyrosequencing platforms (454/Roche, Solexa/Illumina) enable very high-throughput DNA sequencing, up to ~1 billion bases per run
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Host-pathogen studies in the post-genomic era.
PMID 11178231 · PMC138846 · Genome biology · 2000 · 7 claims · 7 setups
DNA arrays have been used to study host and/or pathogen gene expression for four viruses (HCMV, HHV8, HIV-1, HPV31) and two bacteria (Listeria monocytogenes, Salmonella)
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An Asilomar moment.
PMID 12372138 · PMC244904 · Genome biology · 2002 · 7 claims · 3 setups
The current push to restrict genomics/pathogen research funding and publication due to bioterrorism fears parallels the 1975 Asilomar Conference response to recombinant DNA risks.
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Bcipep: a database of B-cell epitopes.
PMID 15921533 · PMC1173103 · BMC genomics · 2005 · 8 claims · 2 setups
Bcipep is a comprehensive database of experimentally determined linear B-cell epitopes compiled from literature and other public databases
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Thirty years into the genomics era: tumor viruses led the way.
PMID 17940630 · PMC1994808 · The Yale journal of biology and medicine · 2006 · 8 claims · 8 setups
Restriction endonuclease-based analysis and sequencing of small tumor virus genomes (SV40, phiX174) established the technical framework later used to sequence bacterial and human genomes
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Antigenic diversity, transmission mechanisms, and the evolution of pathogens.
PMID 19847288 · PMC2759524 · PLoS computational biology · 2009 · 8 claims · 3 setups
Three distinct infection types (A, B, C) emerge as maxima in the pathogen fitness landscape, each with characteristic within-host dynamics, contact network structure, and transmission mode
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Molecular genomic approaches to infectious diseases in resource-limited settings.
PMID 19855820 · PMC2745561 · PLoS medicine · 2009 · 8 claims · 5 setups
Researchers in most developing countries lack the technology, resources, and capacity to participate fully in genomics research.