Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Ectopic CD11c Drives SMAD3-Mediated Aberrant Antigen Presentation and Epithelial-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma.
PMID 41799568 · PMC12963642 · Cancer communications (London, England) · 2026 · 8 claims · 13 setups
An ESCC epithelial cell subcluster with ectopic CD11c (ITGAX) expression, found in both mice and humans, exhibits concurrent impaired antigen presentation and EMT phenotypes
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Reciprocal regulation of fibroblast-macrophage equilibrium governs skin integrity.
PMID 41760904 · PMC13043295 · Nature immunology · 2026 · 8 claims · 8 setups
Dpt+ fibroblasts are required to maintain skin macrophage populations in vivo; their depletion reduces CD64+ and CD11c+ macrophages
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GATA2 controls alveolar macrophage inflammatory gene expression and metabolic function.
PMID 41712459 · PMC13134736 · JCI insight · 2026 · 8 claims · 8 setups
GATA2 deficiency promotes enhanced inflammatory gene expression and metabolic dysfunction in alveolar macrophages in response to type 2 stimuli
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Has reproduction · 48
Irisin ameliorates obesity and insulin resistance via adipose tissue IL-33 and regulatory T cells.
PMID 41933175 · PMC13052164 · Nature metabolism · 2026 · 8 claims · 8 setups
Irisin modulates adipose tissue inflammation by increasing IL-33 production and preserving ST2+ regulatory T cells in white adipose tissues, thereby improving obesity and glucose intolerance.