Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Patient-derived orthotopic xenograft models recapitulate the peritoneal dissemination of pancreatic cancer and delineate its transcriptional and regulatory programs.
PMID 41673768 · PMC12998334 · Journal of experimental & clinical cancer research : CR · 2026 · 6 claims · 8 setups
Organoids derived from malignant effusions of PDAC patients reproducibly generate peritoneal metastases after orthotopic implantation into the pancreas of immunodeficient mice
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A new form of diabetes caused by INS mutations defined by zygosity, stem cell and population data.
PMID 41484206 · PMC12905373 · EMBO molecular medicine · 2026 · 6 claims · 7 setups
INS R6C is a recessive loss-of-function mutation causing diabetes only in homozygous individuals, not a dominant mutation as previously classified.
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Has reproduction · 83
De novo identification of CD4(+) T cell epitopes.
PMID 38658646 · PMC11093748 · Nature methods · 2024 · 7 claims · 8 setups
SABR-IIs (chimeric receptors linking a covalently attached peptide-MHC-II to CD28-CD3ζ signaling domains) present epitopes to CD4+ T cells and induce a readable NFAT-GFP/CD69 signal upon cognate TCR recognition
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Deep-Learning Tool ScVital Enables Species-Agnostic Integration of Cancer Cell States.
PMID 41223329 · PMC13053053 · Cancer research · 2026 · 7 claims · 7 setups
scVital is a variational autoencoder with an adversarially trained discriminator that embeds scRNA-seq data from different species into a species-agnostic latent space to overcome batch effect.