Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 100
The genome of the ant Tetramorium bicarinatum reveals a tandem organization of venom peptides genes allowing the prediction of their regulatory and evolutionary profiles.
PMID 38245722 · PMC10800049 · BMC genomics · 2024 · 8 claims · 8 setups
44 venom peptide genes were identified, distributed across four of the eleven chromosomes and organized in tandem repeat clusters.
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RAId_DbS: mass-spectrometry based peptide identification web server with knowledge integration.
PMID 18954448 · PMC2605478 · BMC genomics · 2008 · 7 claims · 4 setups
Constructed enhanced protein databases integrating annotated SAPs, PTMs, and disease associations for 17 organisms.
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Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum.
PMID 16980117 · PMC7159276 · Lancet (London, England) · 2006 · 8 claims · 5 setups
An SVM classifier trained on serum proteomic profiles discriminated patients with active tuberculosis from controls with clinically overlapping conditions
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Has reproduction · 37
Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength.
PMID 34534438 · PMC8585507 · Immunity · 2021 · 6 claims · 7 setups
TCR signal strength drives dynamic, dose- and time-dependent transcriptional changes in CD4+ T cells while single-cell Nr4a3 activation dynamics remain digital/uniform.
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Has reproduction · 75
PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy.
PMID 33188038 · PMC7668369 · Journal for immunotherapy of cancer · 2020 · 6 claims · 6 setups
The frequency of circulating PD-1+TIGIT+ (DPOS) CD8+ T cells after 1 month of anti-PD-1 therapy is associated with clinical response and overall survival across three independent cohorts.
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Urinary proteomic profiling for diagnostic bladder cancer biomarkers.
PMID 19811072 · PMC3422861 · Expert review of proteomics · 2009 · 8 claims · 8 setups
Single protein biomarkers (e.g., NMP-22, BTA) suffer from high false-positive rates and none have replaced cystoscopy or cytology for bladder cancer detection.
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Has reproduction · 91
De Novo Assembly and Annotation of the Larval Transcriptome of Two Spadefoot Toads Widely Divergent in Developmental Rate.
PMID 31217263 · PMC6686947 · G3 (Bethesda, Md.) · 2019 · 8 claims · 8 setups
De novo transcriptome assemblies were generated for larval P. cultripes and S. couchii, providing new genomic resources for spadefoot toads
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Coiled-coil protein composition of 22 proteomes--differences and common themes in subcellular infrastructure and traffic control.
PMID 16288662 · PMC1322226 · BMC evolutionary biology · 2005 · 7 claims · 5 setups
Proteins with extended coiled-coil domains (>250 amino acids) are largely absent from bacterial genomes but present in archaea and eukaryotes.
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OPTIC: orthologous and paralogous transcripts in clades.
PMID 17933761 · PMC2238935 · Nucleic acids research · 2008 · 6 claims · 7 setups
OPTIC is a database providing gene predictions and orthology assignments for three clades: amniotes (human, dog, mouse, opossum, platypus, chicken), 12 Drosophila species, and 4 Caenorhabditis nematodes.