Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 95
Single-cell transcriptomics and chromatin accessibility profiling elucidate the kidney-protective mechanism of mineralocorticoid receptor antagonists.
PMID 37906287 · PMC10760974 · The Journal of clinical investigation · 2024 · 8 claims · 7 setups
Mineralocorticoid (DOCA) effects are established through open chromatin and target gene expression primarily in principal and connecting tubule cells, and to a lesser extent in distal convoluted tubule (DCT2) cells.
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Genomics against flatulence.
PMID 17635535 · PMC1974822 · Environmental microbiology · 2007 · 8 claims · 8 setups
Methanogenic archaea (not bacteria) in the human gut, chiefly Methanobrevibacter smithii, produce the methane component of intestinal gas, most of which is released via the large intestine (up to 0.5 l day−1) rather than in breath.
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Defining the proteome.
PMID 16356278 · PMC1414090 · Genome biology · 2005 · 8 claims · 8 setups
Integration of multi-omics data is an important step toward a systems-biology approach to the proteome