Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Genomic variability associated with the presence of occult hepatitis B virus in HIV co-infected individuals.
PMID 19889143 · PMC3032083 · Journal of viral hepatitis · 2010 · 7 claims · 8 setups
O-HBV-associated mutations in PreS/S/polymerase regions likely contribute to undetectable HBsAg by interfering with serologic detection, altering antigen secretion, and/or decreasing replicative fitness
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Has reproduction · 76
Transcriptional landscape of repetitive elements in normal and cancer human cells.
PMID 25012247 · PMC4122776 · BMC genomics · 2014 · 8 claims · 8 setups
RepEnrich, a computational method that uses all mapping reads (uniquely mapping plus multi-mapping reads assigned to repetitive element subfamily assemblies/pseudogenomes), quantifies genome-wide repetitive element enrichment
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Molecular and clinical genetics of mitochondrial diseases due to POLG mutations.
PMID 18546365 · PMC2891192 · Human mutation · 2008 · 8 claims · 4 setups
POLG mutations cause at least 6 major heterogeneous phenotypes of neurodegenerative mitochondrial disease (MCHS, Alpers syndrome, ANS, MEMSA, arPEO, adPEO)
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The specificity and polymorphism of the MHC class I prevents the global adaptation of HIV-1 to the monomorphic proteasome and TAP.
PMID 18949050 · PMC2569417 · PloS one · 2008 · 6 claims · 5 setups
Within individual hosts, proteasome and TAP escape mutations in HIV-1 occur frequently
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Has reproduction · 67
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
PMID 34795257 · PMC8602323 · Nature communications · 2021 · 8 claims · 12 setups
PYK2 was identified as a putative IRF5 kinase via a kinase inhibitor library screen in macrophages