Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors.
PMID 18687142 · PMC2546438 · Retrovirology · 2008 · 7 claims · 6 setups
Integrase displays significantly less inter- and intra-subtype amino acid diversity and lower Shannon's entropy than protease or RT.
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Candidate vaccine sequences to represent intra- and inter-clade HIV-1 variation.
PMID 19812689 · PMC2753653 · PloS one · 2009 · 7 claims · 5 setups
Natural CTL immunodominance toward variable proteome regions increases epitope mismatch with challenge strains and recapitulates the escape-driven CTL failure seen in natural infection, contributing to HIV vaccine failure
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Effects of HIV type-1 immune selection on susceptability to integrase inhibitor resistance.
PMID 19918099 · PMC4155129 · Antiviral therapy · 2009 · 8 claims · 6 setups
Primary integrase inhibitor resistance mutations (T66I, E92Q, G140S, Y143C/H/R, Q148H/R/K, N155S/H) were absent in 342 drug-naive individuals, indicating these sites are highly constrained.
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Using DNA microarrays to study host-microbe interactions.
PMID 10998383 · PMC2627958 · Emerging infectious diseases · 2000 · 8 claims · 8 setups
DNA microarrays can measure transcript levels and detect sequence polymorphisms for every gene simultaneously in microbial genomes