Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Comparative genomics of Drosophila and human core promoters.
PMID 16827941 · PMC1779564 · Genome biology · 2006 · 8 claims · 6 setups
Drosophila core promoters contain 298 highly significant (p≤1e-16) non-randomly positioned 8-mers within 100 bp of the TSS, grouped into 15 distinct DNA motifs
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Differentiation of core promoter architecture between plants and mammals revealed by LDSS analysis.
PMID 17855401 · PMC2094075 · Nucleic acids research · 2007 · 7 claims · 8 setups
LDSS analysis identifies octamer sequences with localized distribution profiles as promoter constituents, classifiable into groups (REG, TATA, Inr, Kozak, CpG, Y Patch)
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Evolution of motif variants and positional bias of the cyclic-AMP response element.
PMID 17288573 · PMC1796609 · BMC evolutionary biology · 2007 · 8 claims · 4 setups
Canonical CRE positional bias toward the -1 to -150 bp TSS region is present in vertebrates (human, mouse, rat, chicken, frog, zebrafish) but absent in sea squirt, fruit fly and worm.