Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 93
Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in OriLyt.
PMID 36645269 · PMC9927211 · Microbiology spectrum · 2023 · 8 claims · 8 setups
An enhancer-like element in OriLyt (RNA4.9 promoter) is extraordinarily enriched in H3K27Ac compared to other viral loci.
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Has reproduction · 93
7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress.
PMID 39952919 · PMC11828898 · Nature communications · 2025 · 8 claims · 8 setups
Heat shock induces de novo transcription and nuclear accumulation of 7SL RNA together with SRP proteins, which then bind chromatin at promoters
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A conserved hormonal signalling-H2A.Z axis rapidly reorganizes 3D chromatin interactions in adipocyte thermogenesis.
PMID 42014869 · PMC13218939 · Nature metabolism · 2026 · 8 claims · 8 setups
β3-AR signalling rapidly reorganizes chromatin loops within 4 hours of stimulation
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Cohesin regulates alternative splicing.
PMID 36857449 · PMC9977177 · Science advances · 2023 · 7 claims · 8 setups
Cohesin regulates alternative splicing independently of its effects on transcription.
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Hypoxia leads to reduced mito-nuclear gene expression and increased mtDNA transcriptional pausing in human cells.
PMID 41507516 · PMC12880982 · Communications biology · 2026 · 8 claims · 6 setups
Hypoxia induces a coordinated downregulation of mito-nuclear OXPHOS gene expression across most human cell lines tested