Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 101

Assay: production ✕ Clear

Impact of genomics on animal agriculture and opportunities for animal health.

PMID 18022262 · PMC7114270 · Trends in biotechnology · 2008 · 8 claims · 7 setups

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Genomics tools (single-gene tests, SNP chips, genomic selection) will speed genetic improvement of livestock production traits

cattle chicken pig snp whole-genome transgenic
The identification and characterization of a novel protein, c19orf10, in the synovium.

PMID 17362502 · PMC1906808 · Arthritis research & therapy · 2007 · 8 claims · 8 setups

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c19orf10 is a novel protein produced in significant amounts by fibroblast-like synoviocytes (FLSs), identified via proteomic analysis

fibroblast-like coli balb chicken two-dimensional recombinant monoclonal
Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.

PMID 18651708 · PMC2699546 · Proteomics · 2008 · 8 claims · 6 setups

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A dermis-based cell-trapped system (DBCTS) with human sebocytes inserted into a subcutaneous tissue chamber creates a humanized acne microenvironment in mice

chamber infiltrated de-epidermized sebocyte cfu sandwich immunofluorescence
Genetic analysis of 10 unrelated Korean families with p22-phox-deficient chronic granulomatous disease: an unusually identical mutation of the CYBA gene on Jeju Island, Korea.

PMID 19949658 · PMC2775850 · Journal of Korean medical science · 2009 · 8 claims · 4 setups

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All 12 analyzed CGD patients from 10 unrelated Jeju families carry an identical homozygous c.7C>T substitution in exon 1 of CYBA, predicted to cause a nonsense mutation (p.Q3X)

peripheral genomic dhr western rt-pcr
The oxazolidinone derivative locostatin induces cytokine appeasement.

PMID 19917702 · PMC2799496 · Journal of immunology (Baltimore, Md. : 1950) · 2009 · 7 claims · 7 setups

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RKIP is differentially localized (not differentially expressed) on the proteomic map after in vivo T cell recall compared to resting state

ot-i splenocytes fractions serum intracellular proteomics sds-page
Multimodal techniques for diagnosis and prognosis of Alzheimer's disease.

PMID 19829371 · PMC2810658 · Nature · 2009 · 8 claims · 8 setups

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AD pathology accumulates for approximately 10-15 years in a preclinical phase before synaptic and neuronal loss manifest as cognitive decline

subjects csf peripheral amyloid structural functional
Characterizing natural variation using next-generation sequencing technologies.

PMID 19801172 · PMC3994700 · Trends in genetics : TIG · 2009 · 8 claims · 8 setups

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Next-generation sequencing enables complete, genome-wide surveys of genetic variation at unprecedented resolution, overcoming limitations of genotyping panels and microarrays.

pichia individuals saccharomyces individual whole-genome partial comparative
Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor.

PMID 19657311 · PMC2767399 · Pancreas · 2009 · 8 claims · 6 setups

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A homozygous P86S mutation in GCGR is associated with hyperglucagonemia and α cell hyperplasia in the patient

patient's hek293 pancreatic sanger radioligand camp
From forest to farm: the impact of a broad spectrum of lifestyles on the porcine gut microbiota.

PMID 41810129 · PMC12969317 · Current research in microbial sciences · 2026 · 8 claims · 6 setups

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Dietary variables had the largest effect on microbiota composition among lifestyle factors tested

faecal 16s microbiota 16s volatile faecal
Capsular specificity in temperate phages of Klebsiella pneumoniae is driven by diverse receptor-binding enzymes.

PMID 42048315 · PMC13123978 · PLoS biology · 2026 · 8 claims · 5 setups

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Capsular specificity in temperate K. pneumoniae phages is driven by structurally diverse prophage-encoded receptor-binding enzymes, including classical β-helix depolymerases, SGNH-domain hydrolases, and structurally novel RBPs.

klebsiella candidate genome-wide prophage capsular
Heritable ER stress impairs mitochondrial metabolism and maintenance of hematopoietic stem cells after low-dose irradiation.

PMID 41675062 · PMC12886522 · iScience · 2026 · 8 claims · 8 setups

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Proliferating 20 mGy-irradiated HSC exhibit oxidative stress and altered metabolism with increased mitochondrial ROS and mitochondrial Ca2+ overload compared to non-irradiated HSC

cd45.1 hsc hspc-enriched bone flow carbonylation
Splice-switching of the oncogenic BCS1L isoform suppresses ovarian cancer progression by disrupting mitochondrial function.

PMID 41771836 · PMC13039997 · Cell death & disease · 2026 · 7 claims · 8 setups

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BCS1L is alternatively spliced into a full-length isoform (BCS1L-L) and an exon 2-skipped short isoform (BCS1L-S)

tcga-ov ovarian clinical fte187 gsea single-cell qpcr
Genomic capacities for Reactive Oxygen Species metabolism across marine phytoplankton.

PMID 37098087 · PMC10128935 · PloS one · 2023 · 8 claims · 3 setups

Has reproduction · 38

Genes encoding superoxide (O2•−) scavenging are ubiquitous across phytoplankton, but their fractional gene allocation decreases with increasing cell radius, consistent with a nearly fixed core gene set.

diverse annotated same comparative enzyme trait
Gene Ontology annotations: what they mean and where they come from.

PMID 18460184 · PMC2367625 · BMC bioinformatics · 2008 · 7 claims · 3 setups

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A GO annotation is a formal statement linking a gene product type to a molecular function, biological process, or cellular component type, based on experimental observations or inferences.

extract embryo preimplantation enzymatic mutational immunofluorescence
Proposed methods for testing and selecting the ERCC external RNA controls.

PMID 16266432 · PMC1325234 · BMC genomics · 2005 · 8 claims · 5 setups

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A consortium-developed, standardized set of external RNA control transcripts can be used to assess technical performance in gene expression assays (microarray and QRT-PCR)

candidate linearized transcripts pools sequence transcription quality
Structural modeling and functional characterization of a novel gain-of-function TLR8 variant causing severe inflammatory syndrome.

PMID 41729082 · PMC12956005 · JCI insight · 2026 · 8 claims · 8 setups

Has reproduction · 89

TLR8 A518T is a gain-of-function variant that enhances NF-κB activation and increases secretion of proinflammatory cytokines upon stimulation compared with WT TLR8

plasma pbmcs expressing tlr8 targeted plasma quantitative
Numb prevents a complete epithelial-mesenchymal transition by modulating Notch signalling.

PMID 29187638 · PMC5721160 · Journal of the Royal Society, Interface · 2017 · 8 claims · 8 setups

Has reproduction · 49

Numb/Numbl acts as a 'phenotypic stability factor' (PSF) that inhibits a complete EMT by stabilizing the hybrid E/M phenotype

single-cell lattice h1975 ode-based multi-cell sirna
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.

PMID 33086062 · PMC7649750 · Cell reports · 2020 · 8 claims · 8 setups

Has reproduction · 59

KMT2D is a potent tumor suppressor in melanoma

hmel-brafv600e tyr-creert2 tma kmt2d pooled xenograft genetically
Phenotypic and Genotypic Characteristics of Shiga Toxin-Producing Escherichia coli Isolated from Surface Waters and Sediments in a Canadian Urban-Agricultural Landscape.

PMID 27092297 · PMC4820441 · Frontiers in cellular and infection microbiology · 2016 · 6 claims · 8 setups

Has reproduction · 89

STEC prevalence in surface water varies by watershed and by season in the Lower Mainland of British Columbia.

surface sediment isolate presumptive hydrophobic stx monoplex
The genome of the ant Tetramorium bicarinatum reveals a tandem organization of venom peptides genes allowing the prediction of their regulatory and evolutionary profiles.

PMID 38245722 · PMC10800049 · BMC genomics · 2024 · 8 claims · 8 setups

Has reproduction · 100

44 venom peptide genes were identified, distributed across four of the eleven chromosomes and organized in tandem repeat clusters.

tetramorium bicarinatum vpg venom whole-genome blast gene

Experiments

Impact of genomics on animal agriculture and opportunities for animal health.

The identification and characterization of a novel protein, c19orf10, in the synovium.

Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.

Genetic analysis of 10 unrelated Korean families with p22-phox-deficient chronic granulomatous disease: an unusually identical mutation of the CYBA gene on Jeju Island, Korea.

The oxazolidinone derivative locostatin induces cytokine appeasement.

Multimodal techniques for diagnosis and prognosis of Alzheimer's disease.

Characterizing natural variation using next-generation sequencing technologies.

Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor.

From forest to farm: the impact of a broad spectrum of lifestyles on the porcine gut microbiota.

Capsular specificity in temperate phages of Klebsiella pneumoniae is driven by diverse receptor-binding enzymes.

Heritable ER stress impairs mitochondrial metabolism and maintenance of hematopoietic stem cells after low-dose irradiation.

Splice-switching of the oncogenic BCS1L isoform suppresses ovarian cancer progression by disrupting mitochondrial function.

Genomic capacities for Reactive Oxygen Species metabolism across marine phytoplankton.

Gene Ontology annotations: what they mean and where they come from.

Proposed methods for testing and selecting the ERCC external RNA controls.

Structural modeling and functional characterization of a novel gain-of-function TLR8 variant causing severe inflammatory syndrome.

Numb prevents a complete epithelial-mesenchymal transition by modulating Notch signalling.

Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.

Phenotypic and Genotypic Characteristics of Shiga Toxin-Producing Escherichia coli Isolated from Surface Waters and Sediments in a Canadian Urban-Agricultural Landscape.

The genome of the ant Tetramorium bicarinatum reveals a tandem organization of venom peptides genes allowing the prediction of their regulatory and evolutionary profiles.