Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Multidimensional proteomics analysis of amniotic fluid to provide insight into the mechanisms of idiopathic preterm birth.
PMID 18431506 · PMC2315798 · PloS one · 2008 · 7 claims · 7 setups
A novel 5-peak SELDI proteomic signature (Q-profile) in the 10-12.5 kDa mass range identifies a subgroup of women at risk for preterm birth without intra-amniotic inflammation or bleeding.
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Differential proteome analysis of the preeclamptic placenta using optimized protein extraction.
PMID 19756160 · PMC2742651 · Journal of biomedicine & biotechnology · 2010 · 8 claims · 5 setups
Solubilization with urea/CHAPS combined with dichloromethane/methanol or acidified acetone precipitation gives the best 2D-PAGE protein separation for placental tissue
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Proteomic profiling of urine identifies specific fragments of SERPINA1 and albumin as biomarkers of preeclampsia.
PMID 18984079 · PMC2679897 · American journal of obstetrics and gynecology · 2008 · 8 claims · 7 setups
Women with severe preeclampsia present a unique urinary proteomic fingerprint distinguishable from controls.
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Novel approaches for mechanistic understanding and predicting preeclampsia.
PMID 19836839 · PMC2790420 · Journal of reproductive immunology · 2009 · 8 claims · 6 setups
The classic two-stage hypothesis (Stage I poor placental perfusion causing Stage II maternal symptoms) needs reevaluation because reduced perfusion alone may be insufficient to cause PE.