Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 99
Evaluation of taxonomic classification and profiling methods for long-read shotgun metagenomic sequencing datasets.
PMID 36513983 · PMC9749362 · BMC bioinformatics · 2022 · 8 claims · 7 setups
Long-read classifiers generally performed best among the 11 methods tested
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Phylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms?
PMID 15287975 · PMC507878 · Genome biology · 2004 · 8 claims · 6 setups
3,848 Arabidopsis proteins were identified as likely plant-specific based on phylogenetic profiling and EST confirmation in multiple plant species
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How bacterial communities expand functional repertoires.
PMID 17238278 · PMC1750926 · PLoS biology · 2006 · 8 claims · 7 setups
The human microbiome contains roughly 100 times as many genes as does the human genome
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The 32nd Annual Congress of the Society of Critical Care Medicine, 28 January - 2 February 2003, San Antonio, USA.
PMID 12720569 · PMC270663 · Critical care (London, England) · 2003 · 8 claims · 8 setups
Proteomics is more useful than genomics for identifying regulatory pathways and druggable targets in disease because transcriptional responses to different stimuli often converge while protein interaction networks reveal distinct regulatory nodes
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Microbial genomics: from sequence to function.
PMID 10998380 · PMC2627950 · Emerging infectious diseases · 2000 · 8 claims · 4 setups
Whole-genome shotgun sequencing (sequencing and assembly of random genome fragments), first demonstrated with Haemophilus influenzae in 1995, is now the method of choice for sequencing most genomes, including the human genome.
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The Proteomics Identifications database: 2010 update.
PMID 19906717 · PMC2808904 · Nucleic acids research · 2010 · 8 claims · 6 setups
PRIDE has become one of the main repositories for MS-based proteomics data, with substantial growth in data holdings over the last two years.
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From single cells to whole organisms.
PMID 16420683 · PMC1414103 · Genome biology · 2005 · 8 claims · 8 setups
The genetic-interaction map in S. cerevisiae is roughly four times as complex as the protein-protein interaction map, and genetic interactions do not overlap with physical interactions but instead predict functional neighborhoods
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Glycomic analysis: an array of technologies.
PMID 19728746 · PMC3443568 · ACS chemical biology · 2009 · 8 claims · 8 setups
Glycosylation is the most prevalent protein post-translational modification, occurring on at least 50% of all proteins
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Proteomics and genomics: perspectives on drug and target discovery.
PMID 18302945 · PMC2386992 · Current opinion in chemical biology · 2008 · 8 claims · 8 setups
Protein kinases account for approximately 25% of research and development projects in biotechnology and pharma