Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 4

System / cell line: hsc ✕ Assay: promoter ✕ Clear

Motif discovery in promoters of genes co-localized and co-expressed during myeloid cells differentiation.

PMID 19059999 · PMC2632922 · Nucleic acids research · 2009 · 6 claims · 8 setups

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A novel multi-step computational method (built on approximate pattern enumeration, binomial over-representation scoring with FDR correction, and k-medoids clustering) can identify over-represented motifs in a selected set of promoters relative to a background promoter set.

myeloid reference selected genome-localized microarray promoter k-medoids
Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation.

PMID 41477881 · PMC12850507 · Science (New York, N.Y.) · 2026 · 8 claims · 8 setups

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A haplotype at the 17q22 locus, tagged by the noncoding variant rs17834140-T, is a causal protective variant against CHIP and myeloid malignancies

population hspcs cd34+cd45ra-cd90+ heterozygous gwas atac-seq crispr
RNA-binding protein LARP6 coordinates hepatic stellate cell activation and liver fibrosis.

PMID 41746718 · PMC13078889 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups

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LARP6 is upregulated in activated hepatic stellate cells (A1/A2 subclusters) in human MASH and MetALD livers

hepatic liver recombinant activated eclip ribosome single-nucleus
Epigenetic profiling of hematopoietic stem cells from male mice identifies KDR and PU.1 as regulators of aging transcriptome and caloric restriction response.

PMID 41720793 · PMC13035812 · Nature communications · 2026 · 8 claims · 8 setups

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Lifelong CR reduces white blood cell production and shifts hematopoiesis toward myeloid and thrombo-erythroid lineages while suppressing lymphoid output

peripheral sorted young aged complete flow bulk

Experiments

Motif discovery in promoters of genes co-localized and co-expressed during myeloid cells differentiation.

Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation.

RNA-binding protein LARP6 coordinates hepatic stellate cell activation and liver fibrosis.

Epigenetic profiling of hematopoietic stem cells from male mice identifies KDR and PU.1 as regulators of aging transcriptome and caloric restriction response.