Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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SNP@Promoter: a database of human SNPs (single nucleotide polymorphisms) within the putative promoter regions.
PMID 18315851 · PMC2259403 · BMC bioinformatics · 2008 · 8 claims · 4 setups
SNP@Promoter is a database of human SNPs within putative promoter regions and predicted transcription factor binding sites
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TRED: a transcriptional regulatory element database, new entries and other development.
PMID 17202159 · PMC1899102 · Nucleic acids research · 2007 · 8 claims · 3 setups
TRED collects mammalian cis- and trans-regulatory elements together with experimental evidence, mapped onto assembled genomes
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Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment.
PMID 16925837 · PMC1810552 · Genome biology · 2006 · 6 claims · 3 setups
Promoter predictors that combine promoter prediction with gene prediction (N-SCAN, Fprom) achieve better performance than pure ab initio promoter predictors, mainly by reducing the promoter search space and false positives
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Has reproduction · 94
SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells.
PMID 32770939 · PMC7430845 · BMC genomics · 2020 · 6 claims · 6 setups
SOX10 binds proximal promoters genome-wide in Schwann cells, with ChIP-seq signal concentrated directly over TSSs that are also marked by H3K4me3
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Methylation of class II transactivator gene promoter IV is not associated with susceptibility to multiple sclerosis.
PMID 18606010 · PMC2464579 · BMC medical genetics · 2008 · 6 claims · 4 setups
Methylation of the MHC2TA promoter pIV is not associated with MS susceptibility; no methylation was detected in any twin sample regardless of disease status
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Has reproduction
Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data.
PMID 35473573 · PMC9044877 · Genome biology · 2022 · 8 claims · 8 setups
Combining multiple enhancer-definition and enhancer-gene link data sources yields 1860 genome-wide EnTDefs covering >500 cell types
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In silico comparative genomic analysis of GABAA receptor transcriptional regulation.
PMID 17603907 · PMC1934366 · BMC genomics · 2007 · 8 claims · 8 setups
Previously unreported putative promoters were identified for the β2, γ1, γ3, ε, θ and π GABA A receptor subunit genes
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ABS: a database of Annotated regulatory Binding Sites from orthologous promoters.
PMID 16381947 · PMC1347478 · Nucleic acids research · 2006 · 7 claims · 6 setups
ABS is a public database of experimentally identified TF binding sites conserved in orthologous vertebrate gene promoters, manually curated from the literature.
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miRGen 2.0: a database of microRNA genomic information and regulation.
PMID 19850714 · PMC2808909 · Nucleic acids research · 2010 · 7 claims · 6 setups
miRGen 2.0 is a database providing comprehensive information about the genomic position of human and mouse microRNA coding transcripts and their regulation by transcription factors
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MutScreener: primer design tool for PCR-direct sequencing.
PMID 16845093 · PMC1538803 · Nucleic acids research · 2006 · 8 claims · 4 setups
MutScreener is a web-based application that automates PCR-direct sequencing assay design by annotating gene structure and designing PCR and sequencing primers.
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Has reproduction · 49
oPOSSUM-3: advanced analysis of regulatory motif over-representation across genes or ChIP-Seq datasets.
PMID 22973536 · PMC3429929 · G3 (Bethesda, Md.) · 2012 · 8 claims · 6 setups
oPOSSUM-3 is a web-accessible system that identifies over-represented TFBS and TFBS families in DNA sequences of co-expressed genes or in sequences from high-throughput methods such as ChIP-Seq.
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Has reproduction · 63
A worldwide map of swine short tandem repeats and their associations with evolutionary and environmental adaptations.
PMID 33892623 · PMC8063339 · Genetics, selection, evolution : GSE · 2021 · 8 claims · 8 setups
Identified 878,967 polymorphic STRs (pSTRs) from 394 deep-sequenced pig/Suidae genomes, the largest pSTR repository in pigs to date