Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Protein microarray technology.
PMID 17126887 · PMC1828913 · Mechanisms of ageing and development · 2007 · 8 claims · 8 setups
Protein microarrays enable high-throughput characterization of protein biochemical activities across an entire proteome in a single experiment
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Integrating proteomic, transcriptional, and interactome data reveals hidden components of signaling and regulatory networks.
PMID 19638617 · PMC2889494 · Science signaling · 2009 · 8 claims · 6 setups
Pathway reconstruction can be modeled as a prize-collecting Steiner tree problem, balancing penalties for excluding terminal nodes against costs for including edges, controlled by a parameter β.
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The integrated world of functional genomics.
PMID 12537543 · PMC151279 · Genome biology · 2003 · 8 claims · 8 setups
Integrating chromatin immunoprecipitation (promoter-binding) data with expression data reveals the yeast cell-cycle transcriptional regulatory network, including network motifs such as autoregulation, multi-component loops, and feedforward loops.
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A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae.
PMID 19917080 · PMC2784802 · BMC genomics · 2009 · 8 claims · 4 setups
Genome-wide deletion screening identified 149 genes whose deletion causes NiSO4 sensitivity and 119 genes whose deletion confers NiSO4 resistance.
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An NSP2-MYB module orchestrates flavonoid biosynthesis and nodule symbiosis.
PMID 41643674 · PMC7619063 · Current biology : CB · 2026 · 8 claims · 8 setups
NSP1 and NSP2 promote expression of flavonoid biosynthesis genes during nutrient starvation and rhizobial symbiosis in Medicago truncatula
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Network inference and network response identification: moving genome-scale data to the next level of biological discovery.
PMID 20174676 · PMC3087299 · Molecular bioSystems · 2010 · 8 claims · 8 setups
Cellular response to a signal is assumed to involve only specific TRN modules (conditionally active subnetworks) rather than the entire network, providing quantitative tractability
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Cryptosporidium: genomic and biochemical features.
PMID 19187778 · PMC2819285 · Experimental parasitology · 2010 · 8 claims · 8 setups
C. parvum lacks a plastid and mitochondrial genome, unlike other apicomplexans, limiting plastid-targeted drug strategies