Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Immune profiling in a living human recipient of a gene-edited pig kidney.

  PMID 41507576 · PMC12823403 · Nature medicine · 2026 · 8 claims · 8 setups

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  Xenograft experienced early T cell-mediated rejection (Banff grade 2A) within 1 week post-transplant despite profound circulating T cell depletion, likely driven by subtherapeutic immunosuppression and residual CD8+ T cells in lymph nodes.

  xenotransplant recipient kidney integrative single-cell flow

• Spatial cartography of human thymus enables the geopositioning of lineage transcription factors in rare mimetic thymic epithelial cells.

  PMID 41807357 · PMC13102919 · Nature communications · 2026 · 7 claims · 7 setups

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  Generated a high-resolution spatial transcriptomic atlas of human fetal (13,14,17,18w) and paediatric (7w,2y,5y,6y) thymi using Stereo-seq, integrated with scRNA-seq and MACSima/Stereo-CITE proteomics

  fetal paediatric thymus stereo-seq scrna-seq macsima

• Radiogenomics predicts immune microenvironment heterogeneity and response to combination immunotherapy in hepatocellular carcinoma.

  PMID 41555384 · PMC12895822 · Journal of translational medicine · 2026 · 8 claims · 8 setups

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  A parsimonious 2-gene immune-related signature (IRS = 0.425×KPNA2 + 0.302×SMG5) is significantly associated with immune heterogeneity and response to ICI plus anti-angiogenic combination therapy in HCC

  hcc gse202642 paired hcc-derived bulk single-cell immunohistochemistry

• Integration of aged brain multi-omics reveals cross-system mechanisms underlying Alzheimer's disease heterogeneity.

  PMID 41950003 · PMC13244359 · Cell reports · 2026 · 8 claims · 7 setups

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  Multi-omics factor analysis (MOFA) integrating seven omics views from 1,358 ROS/MAP participants identifies cross-omics biological factors relating to AD phenotypes.

  dorsolateral brain postmortem cortex h3k9ac bulk proteomics

• SMART: spatial multi-omic aggregation using graph neural networks and metric learning.

  PMID 41896208 · PMC13031631 · Nature communications · 2026 · 8 claims · 5 setups

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  SMART accurately identifies spatial regions of anatomical structures and is compatible with spatial datasets of any type and number of omics layers

  simulated lymph brain spleen simulated spatial multi-section

• A sequence knowledge-guided deep learning method for single-cell multi-omics translation.

  PMID 41975483 · PMC13185235 · Genome biology · 2026 · 7 claims · 7 setups

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  scProTrans, a deep learning framework combining sequence knowledge (dna2vec gene embeddings, ProtT5 protein embeddings) with a cross-omics attention mechanism, translates single-cell transcriptome data into proteome profiles

  multi-omics pbmcs datasets fully cite-seq cross-technology tri-omics