Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 44
Phased differentiation of γδ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers.
PMID 34721945 · PMC8555559 · Oncoimmunology · 2021 · 7 claims · 6 setups
In tumors, TCRVγnon9 γδ T cells (the majority γδ TIL subset) are quantitatively correlated and aligned with T CD8 cells for differentiation, exhaustion, gene expression profile, and response to immune checkpoint therapy
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Single-Cell Multi-Tissue T Cell Clonal Dynamics Reveal Distinct Immune Coercion Landscapes in MSI and MSS Colorectal Cancer.
PMID 41898550 · PMC13027115 · International journal of molecular sciences · 2026 · 8 claims · 5 setups
Immunotherapy response in CRC is better explained by TCR clonal dynamics (expansion, migration, functional transitions) than by MSI status alone
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Host-derived interleukin-1α drives tumor immunosuppression by reprogramming tumor-associated myeloid cells.
PMID 41547846 · PMC12910057 · NPJ breast cancer · 2026 · 8 claims · 8 setups
Deletion of host Il1α causes rejection/regression of transplanted breast tumors
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VISTA drives pancreatic tumor progression through modulation of the tumor-associated macrophage polarity.
PMID 41776161 · PMC13194722 · Nature communications · 2026 · 8 claims · 8 setups
VISTA deficiency significantly impairs PDAC tumor growth and prolongs survival in murine orthotopic models