Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Metabolic adaptations rewire CD4(+) T cells in a subset-specific manner in human critical illness with and without sepsis.
PMID 41540263 · PMC12864044 · Nature immunology · 2026 · 8 claims · 7 setups
CD4+ T cells in critical illness show subset-specific metabolic plasticity, with regulatory T (Treg) cells preferentially acquiring glycolytic capacity
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Metabolic quiescence of naive-like memory T cells precedes and maintains antigen-specific T cell memory.
PMID 41735532 · PMC12956582 · Nature immunology · 2026 · 8 claims · 8 setups
CD8+ T cells upregulate glycolysis to fuel anabolic needs for proliferation but predominantly use oxidative phosphorylation (OXPHOS) for energy production during the acute phase (days 7-28) after YFV vaccination