Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Single-cell ATAC-seq analysis of human embryoid bodies reveals crucial transcription factor networks involved in early germ layer specification.
PMID 41906160 · PMC13154528 · Cell & bioscience · 2026 · 7 claims · 7 setups
scATAC-seq of human EBs can classify cells into the three germ layers and, via pseudotime analysis, identify 'early committed cells' at the onset of each germ layer.
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Has reproduction · 74
Microglia-containing cerebral organoids derived from induced pluripotent stem cells for the study of neurological diseases.
PMID 36936782 · PMC10014280 · iScience · 2023 · 8 claims · 8 setups
A novel protocol using FGF/EGF/heparin growth factor supplementation and 10% CO2 culture generates cerebral organoids containing neurons, astrocytes, and microglia from iPSCs/hESCs
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Rtf1-dependent transcriptional pausing regulates cardiogenesis.
PMID 41537425 · PMC12807453 · eLife · 2026 · 8 claims · 7 setups
Rtf1 activity is essential for differentiation of the myocardial lineage from mesoderm
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TGFβ-activated PDHB promotes mitochondrial pyruvate metabolism and contributes to human endoderm differentiation via ATP-dependent BRG1.
PMID 41702907 · PMC13022444 · Nature communications · 2026 · 8 claims · 8 setups
DE differentiation requires a TGFβ-driven metabolic switch characterized by reduced lactate production and enhanced TCA cycle activity/oxidative phosphorylation, mediated by PDHB