Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 9

System / cell line: integrated ✕ Assay: qpcr ✕ Clear

Integrated Analysis of Transcriptome and Metabolome Reveals Metabolite Biosynthesis in Pigmented Potatoes.

PMID 41898740 · PMC13026113 · International journal of molecular sciences · 2026 · 7 claims · 7 setups

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Pigmented potato cultivars (DG26, DJ247) accumulate higher levels of flavonoids and linoleic acid derivatives than the white-fleshed cultivar (AG594)

potato bioinformatic untargeted rna-seq rt-qpcr
Decoding the circRNA-miRNA-mRNA regulatory network in hepatitis B virus-driven hepatocellular carcinoma.

PMID 41845440 · PMC13107627 · Cell communication and signaling : CCS · 2026 · 8 claims · 8 setups

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A bioinformatic pipeline combining RNA-seq, circRNA calling, ECDF analysis, PPI, and survival analysis identifies a circRNA-miRNA-mRNA ceRNA network in HBV-integrated HCC cells

hep3b qpcr dysregulated target bulk circrna rt-qpcr
CITED2 is a druggable epigenetic switch coupling neuronal maturation to regenerative decline.

PMID 41731079 · PMC13083982 · EMBO molecular medicine · 2026 · 8 claims · 8 setups

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The transition from immature non-polarized to mature polarized DRG neurons (E12.5-E17.5) is associated with loss of gene expression signatures needed for regenerative growth competence.

drg sciatic rna-seq integrated immunofluorescence
Single-cell RNA-sequencing of dermal fibroblasts demonstrates culture-induced changes and variable persistence of keloid disease features.

PMID 42058918 · PMC13123497 · iScience · 2026 · 7 claims · 6 setups

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Fibroblast culture leads to subtype assimilation, with in vivo heterogeneity persisting only minimally by passage 4

dermal mesenchymal stromal patient-matched single-cell bulk qpcr
5-methylcytosine RNA modification regulators-based patterns and features of immune microenvironment in acute myeloid leukemia.

PMID 38277218 · PMC10911375 · Aging · 2024 · 8 claims · 8 setups

Has reproduction · 93

m5C regulators are differentially expressed between AML and normal samples and correlate with AML prognosis

tcga aml gse12417 bulk mutation methylation
OTX2 inhibits human pluripotent stem cell reprogramming toward 8-cell-like and morula-like states.

PMID 41554740 · PMC12909843 · Nature communications · 2026 · 8 claims · 8 setups

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OTX2 establishes a repressive barrier to the induction of 8CLCs from primed hPSCs

tprx1-egfp otx2-ko primed preimplantation flow bulk single-cell
Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.

PMID 41746734 · PMC13043084 · JCI insight · 2026 · 8 claims · 8 setups

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The dG-MYRF C-terminal frameshift variant undergoes normal homotrimerization, cleavage, and nuclear localization but shows reduced steady-state levels of the C-terminal cleavage product and decreased transcriptional activation of target genes.

arpe-19 myrf rpe e17.5 immunofluorescence computational cycloheximide
Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs.

PMID 41857393 · PMC13061643 · Nature neuroscience · 2026 · 8 claims · 6 setups

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Adult spinal-cord-derived human oligodendroglia and astrocytes, but not microglia, show primed chromatin signatures at HOX loci and a putative SOX10 enhancer.

postmortem induced lentiviral cns single-nucleus nanocut&tag high-resolution
Integrative bulk and single-cell transcriptomics link EZH2 to immunosuppressive programs and tumor-Treg crosstalk in castration-resistant prostate cancer.

PMID 41710887 · PMC12909565 · Frontiers in immunology · 2026 · 8 claims · 8 setups

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Higher EZH2 expression is associated with adverse clinical outcomes in bulk PCa/CRPC cohorts

tcga-prad su2c gse264573 gse137829 bulk scrna-seq ligand-receptor

Experiments

Integrated Analysis of Transcriptome and Metabolome Reveals Metabolite Biosynthesis in Pigmented Potatoes.

Decoding the circRNA-miRNA-mRNA regulatory network in hepatitis B virus-driven hepatocellular carcinoma.

CITED2 is a druggable epigenetic switch coupling neuronal maturation to regenerative decline.

Single-cell RNA-sequencing of dermal fibroblasts demonstrates culture-induced changes and variable persistence of keloid disease features.

5-methylcytosine RNA modification regulators-based patterns and features of immune microenvironment in acute myeloid leukemia.

OTX2 inhibits human pluripotent stem cell reprogramming toward 8-cell-like and morula-like states.

Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.

Single-nucleus epigenomic profiling of the adult human central nervous system unveils epigenetic memory of developmental programs.

Integrative bulk and single-cell transcriptomics link EZH2 to immunosuppressive programs and tumor-Treg crosstalk in castration-resistant prostate cancer.