Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Cohesin regulates alternative splicing.
PMID 36857449 · PMC9977177 · Science advances · 2023 · 7 claims · 8 setups
Cohesin regulates alternative splicing independently of its effects on transcription.
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Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib.
PMID 41860998 · PMC13004010 · Science advances · 2026 · 8 claims · 6 setups
Imatinib treatment induces transcriptional readthrough in K562 CML cells within 1 hour, before detectable gene expression or alternative splicing changes
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Splice-switching of the oncogenic BCS1L isoform suppresses ovarian cancer progression by disrupting mitochondrial function.
PMID 41771836 · PMC13039997 · Cell death & disease · 2026 · 7 claims · 8 setups
BCS1L is alternatively spliced into a full-length isoform (BCS1L-L) and an exon 2-skipped short isoform (BCS1L-S)
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Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.
PMID 19087274 · PMC2656902 · Breast cancer research : BCR · 2008 · 8 claims · 7 setups
MEK5 over-expression promotes a TNF-α resistance phenotype in MCF-7 breast cancer cells
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Modification at HuR(S242) alters HuR localization and proliferative influence.
PMID 18948743 · PMC2704553 · Cell cycle (Georgetown, Tex.) · 2008 · 8 claims · 8 setups
Systematic S→A mutagenesis of the seven hinge-region serines identifies S242 as a novel determinant of HuR subcellular localization