Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 9

System / cell line: e.g ✕ Assay: qrt-pcr ✕ Clear

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.

PMID 33772001 · PMC7998036 · Nature communications · 2021 · 8 claims · 8 setups

Has reproduction · 85

AAMDC is an amplified/overexpressed oncogene in a subgroup of ER-positive breast cancers (IntClust2) associated with poor prognosis

breast luminal sum52pe t-47d immunohistochemistry fluorescence qrt-pcr
The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation.

PMID 34938960 · PMC8664049 · FASEB bioAdvances · 2021 · 8 claims · 8 setups

Has reproduction · 98

BTN1A1 functions as an apical membrane receptor that forms a lipid-droplet secretion complex with the redox enzyme xanthine oxidoreductase (XDH)

mammary rna-seq proteomic qrt-pcr
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau.

PMID 40204713 · PMC11982250 · Nature communications · 2025 · 8 claims · 7 setups

Has reproduction · 91

GRAMD1B is increased in excitatory neurons of human neural organoids (HNOs) carrying the MAPT R406W mutation

neural hno single-cell immunofluorescence western
Enterotoxins A and B produced by Staphylococcus aureus increase cell proliferation, invasion and cytarabine resistance in acute myeloid leukemia cell lines.

PMID 37810000 · PMC10559070 · Heliyon · 2023 · 7 claims · 7 setups

Has reproduction · 88

SEA and SEB treatment increases proliferation of AML cell lines.

aml cancer proliferation cytotoxicity transwell
Identification and validation of a metabolic-related gene risk model predicting the prognosis of lung, colon, and breast cancers.

PMID 39779736 · PMC11711664 · Scientific reports · 2025 · 8 claims · 8 setups

Has reproduction · 74

540 DEGs overlap across breast, colorectal, and lung cancers out of 11,384 DEGs analyzed

breast colorectal lung common microarray kegg protein-protein
Defining human diabetic nephropathy on the molecular level: integration of transcriptomic profiles with biological knowledge.

PMID 18704688 · PMC2597685 · Reviews in endocrine & metabolic disorders · 2008 · 8 claims · 8 setups

Full-text index only

Genetic predisposition determines susceptibility and rate of progression to ESRD in diabetic patients, in addition to environmental factors

kidney proximal pbmcs macrophages gene qrt-pcr immunohistochemistry
Genome-wide analysis of small RNA and novel MicroRNA discovery in human acute lymphoblastic leukemia based on extensive sequencing approach.

PMID 19724645 · PMC2731166 · PloS one · 2009 · 7 claims · 5 setups

Full-text index only

159 novel miRNAs and 116 novel miRNA*s were identified from ALL patient and normal donor small RNA libraries

pooled sequenced analysis predicted small bioinformatic qrt-pcr
Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.

PMID 14519200 · PMC328454 · Genome biology · 2003 · 8 claims · 5 setups

Full-text index only

Annotation of 8,633 high-quality non-mitochondrial/non-ribosomal ESTs shows 57% represent known genes and 43% are unknown or novel, with M15E having the highest proportion of novel ESTs

embryonic high-quality unique m15e est sequence comparative
Comprehensive analysis of peroxisome proliferator-activated receptors to predict the drug resistance, immune microenvironment, and prognosis in stomach adenocarcinomas.

PMID 38529307 · PMC10962337 · PeerJ · 2024 · 8 claims · 8 setups

Has reproduction · 58

PPARA, PPARD and PPARG are more abnormally expressed in STAD samples and cell lines compared to most of 32 cancer types in TCGA

cancer tcga-stad stomach ges1 rna-seq pearson gsva

Experiments

The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer.

The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation.

GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau.

Enterotoxins A and B produced by Staphylococcus aureus increase cell proliferation, invasion and cytarabine resistance in acute myeloid leukemia cell lines.

Identification and validation of a metabolic-related gene risk model predicting the prognosis of lung, colon, and breast cancers.

Defining human diabetic nephropathy on the molecular level: integration of transcriptomic profiles with biological knowledge.

Genome-wide analysis of small RNA and novel MicroRNA discovery in human acute lymphoblastic leukemia based on extensive sequencing approach.

Annotation and analysis of 10,000 expressed sequence tags from developing mouse eye and adult retina.

Comprehensive analysis of peroxisome proliferator-activated receptors to predict the drug resistance, immune microenvironment, and prognosis in stomach adenocarcinomas.