Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 10

System / cell line: genetic ✕ Assay: qrt-pcr ✕ Clear

Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass.

PMID 18443592 · PMC2742198 · Nature genetics · 2008 · 8 claims · 8 setups

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Osteoglycin (Ogn) is a major candidate regulator of rat LVM, with increased Ogn protein expression associated with elevated LVM

heart ogn cos-1 neonatal eqtl quantitative genome-wide
miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis.

PMID 41811946 · PMC12978216 · Science advances · 2026 · 8 claims · 8 setups

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miR-203 is required for a timely totipotency-to-pluripotency transition during early mouse embryogenesis

preimplantation 8-cell mice mir-203 qrt-pcr genotyping time-lapse
Comprehensive immune profiling reveals IFN-γ signaling in T cells mediates parasite phagocytosis in a rodent malaria model.

PMID 41810957 · PMC13059739 · mBio · 2026 · 8 claims · 8 setups

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IFN-γ signaling in T cells contributes to the development of malaria-associated lung pathology

lungs pbnk65-infected cell-specific lung flow time-series qrt-pcr
Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.

PMID 30503143 · PMC6327112 · Cell stem cell · 2019 · 8 claims · 8 setups

Has reproduction · 30

Single-cell transcriptomic analysis of GBA-N370S iPSC-derived dopamine neurons identifies a progressive axis of gene expression variation leading to endoplasmic reticulum stress.

facs-purified ipsc-derived core bulk single-cell facs
TGFβ-activated PDHB promotes mitochondrial pyruvate metabolism and contributes to human endoderm differentiation via ATP-dependent BRG1.

PMID 41702907 · PMC13022444 · Nature communications · 2026 · 8 claims · 8 setups

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DE differentiation requires a TGFβ-driven metabolic switch characterized by reduced lactate production and enhanced TCA cycle activity/oxidative phosphorylation, mediated by PDHB

escs crispr flow qrt-pcr
Bisphenol a exposure and major depressive disorder: an integrative analysis combining network toxicology, molecular docking, genetic epidemiology, and transcriptomic validation.

PMID 41912493 · PMC13039830 · Translational psychiatry · 2026 · 8 claims · 8 setups

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571 shared targets identified between BPA-associated (2554) and MDD-associated (4661) genes

gene shared gwas gabaergic network ppi mendelian
Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.

PMID 41080564 · PMC12510942 · Frontiers in immunology · 2025 · 8 claims · 8 setups

Has reproduction · 85

Seven key immune-related genes (RNF165, SNCA, SRGN, MARCO, STEAP4, SIGLEC9, TKT) are associated with HCM by intersecting DEGs with MR-identified eQTLs

left eqtl degs merged bulk two-sample functional
SLC25A37 as a novel therapeutic target for benign prostatic hyperplasia: integrative analyses of single-cell RNA sequencing and genome-wide association studies.

PMID 41726128 · PMC12917586 · Open medicine (Warsaw, Poland) · 2026 · 8 claims · 8 setups

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SLC25A37 is causally associated with increased BPH risk, supported by MR, Bayesian colocalization, and reverse MR analyses

prostate gwas eqtl bph single-cell mendelian bayesian
RNA Editing Alterations Define Disease Manifestations in the Progression of Experimental Autoimmune Encephalomyelitis (EAE).

PMID 36429012 · PMC9688714 · Cells · 2022 · 7 claims · 7 setups

Has reproduction · 37

RNA-editing events mediated by APOBEC and ADAR deaminases are significantly reduced throughout the course of EAE disease progression

brain rna-edited brain-isolated naïve rna-seq pathway pcr
Enterotoxins A and B produced by Staphylococcus aureus increase cell proliferation, invasion and cytarabine resistance in acute myeloid leukemia cell lines.

PMID 37810000 · PMC10559070 · Heliyon · 2023 · 8 claims · 8 setups

Has reproduction · 88

SEA and SEB treatment increases cell proliferation in AML cell lines

aml cgp differentially proliferation culture transwell

Experiments

Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass.

miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis.

Comprehensive immune profiling reveals IFN-γ signaling in T cells mediates parasite phagocytosis in a rodent malaria model.

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.

TGFβ-activated PDHB promotes mitochondrial pyruvate metabolism and contributes to human endoderm differentiation via ATP-dependent BRG1.

Bisphenol a exposure and major depressive disorder: an integrative analysis combining network toxicology, molecular docking, genetic epidemiology, and transcriptomic validation.

Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.

SLC25A37 as a novel therapeutic target for benign prostatic hyperplasia: integrative analyses of single-cell RNA sequencing and genome-wide association studies.

RNA Editing Alterations Define Disease Manifestations in the Progression of Experimental Autoimmune Encephalomyelitis (EAE).

Enterotoxins A and B produced by Staphylococcus aureus increase cell proliferation, invasion and cytarabine resistance in acute myeloid leukemia cell lines.